Sadly, two months on Valcyte appears to be no where near enough for PWCs. I'm thinking a year is pretty optimistic. From what I'm hearing, 18mo+ seems to be the effective time period. I have a couple of (uneducated) ideas for why that would be. First, most of us probably have neurological infections (hence the neurological symptoms) and getting medication past the brain-blood barrier isn't easy. Maybe it takes that long to get enough medication into the brain to deal effectively with the infection. Second, Valcyte stops replication of the virus, but does not directly kill it. You still have to wait for the infected cells to die a natural death. While you're waiting for that, you have to keep the infected cells from replicating. Maybe some of the infected cells are fairly long-lived, so it takes a long time to ensure you've knocked the infection down enough for our messed up immune systems to keep the virus latent.