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Evidence Aside, Drugs First Choice for Insomnia

Discussion in 'Other Health News and Research' started by shrewsbury, May 26, 2010.

  1. shrewsbury

    shrewsbury member

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    By Kristina Fiore, Staff Writer, MedPage Today
    Published: May 25, 2010
    Reviewed by Dori F. Zaleznik, MD; Associate Clinical Professor of Medicine, Harvard Medical School, Boston and
    Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
    Earn CME/CE credit for reading medical news

    [sb: my bolds]

    Action Points

    * Explain that a survey found physicians tend to skip the recommended first-line, nonpharmacologic therapies for insomnia, typically prescribing pharmaceuticals instead.

    * Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal.

    NEW ORLEANS -- Evidence-based recommendations to the contrary, few physicians prescribe nonpharmacologic interventions as first-line therapy for insomnia, researchers said here.

    Nearly three-quarters of surveyed physicians reported writing prescriptions for sleep medications as their primary course of treatment, Meghan Rieu-Werden, a research assistant at Massachusetts General Hospital, and colleagues reported during a poster session at the American Psychiatric Association meeting.

    Many treatment guidelines recommend nonpharmacologic interventions as first-line treatment for insomnia, regardless of the cause or associated medical and psychiatric conditions, according to the researchers.

    These interventions include cognitive therapy, cognitive behavioral therapy, relaxation therapy, stress reduction therapy, and sleep hygiene education (SHE), all of which have all been shown to be effective monotherapy.

    Sleep hygiene education is particularly recommended, Rieu-Werden said. It includes going to bed and waking up at the same time every day, limiting the quantity or adjusting the timing of caffeine and alcohol intake, engaging in regular exercise, adjusting the timing of exercise, and implementing relaxation techniques.


    Don Hilty, MD, of the University of California Davis, who was not involved in the study, said these elements "should be common sense, but some patients need reminders."

    To identify practice gaps in the treatment of insomnia, the researchers surveyed 500 healthcare providers who attended a psychopharmacology course -- 40.2% were psychiatrists, 9.4% were nonpsychiatrist physicians, 18.8% were prescribing nurses, and 5% were nonprescribers. It was not possible to identify 26.6% of respondents from the data they provided.

    All participants answered three open-ended clinical questions based on a case vignette, which described a hypothetical patient presenting with major depressive disorder. The patient returns for three visits over the next three months.

    Participants were asked to come up with a diagnosis, provide an initial treatment course, and a treatment for insomnia.

    Rieu-Werden said the study focused on the treatment of insomnia.

    They found that the majority of providers listed pharmacologic monotherapy as their first-line intervention (73.19%). These included hypnotic drugs such as eszopiclone (Lunesta) and zolpidem (Ambien).

    Just 2.22% ordered nonpharmaceutical interventions as their primary treatment.

    About a quarter used a combination of pharmacologic and nonpharmacologic therapies (24.6%) as first-line treatment.


    Other nonpharmacologic interventions survey respondents reported using were melatonin and light box therapy as well.

    The researchers said that survey respondents may have underutilized the sleep hygiene intervention because the hypothetical patient's insomnia returned while taking antidepressants. Thus, many may have assumed that the medication was the cause of the insomnia, Rieu-Werden said.

    She added that the results may also have been confounded because participants were attending a psychopharmacology course.

    Still, Rieu-Werden and colleagues concluded that the majority of healthcare providers don't use nonpharmacologic interventions as primary therapy in insomnia, despite guideline recommendations.

    She said healthcare providers would benefit from educational activities that address various treatments for insomnia.

    Hilty agreed. "Psychiatrists and primary care physicians need to know more about nonpharmaceutical treatments, or try using medications and other interventions in combination if one is not working," he said.

    He also agreed that sleep hygiene generally makes "common sense" as a first-line remedy, but "a more chronic or persistent issue may require cognitive behavioral therapy or cognitive treatment -- something with more impact."

    Rieu-Werden also said that further research needs to be done to determine what influences diagnostic and treatment choices.

    The researchers reported no conflicts of interest. Hilty had no disclosures.

    Primary source: American Psychiatric Association
    Source reference:
    Rieu-Werden ML, et al "Underutilization of nonpharmacologic interventions for insomnia by healthcare providers" APA 2010; Abstract NR2-59.
     
  2. starryeyes

    starryeyes Senior Member

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    Bay Area, California
    I have to say I like this title which shows this much on the front Forum page:


    Evidence Aside, Drugs First
    :D
     
  3. HopingSince88

    HopingSince88 Senior Member

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    Maine
    Two members of my extended family are drug reps. These reps make big money and have huge expense accounts. I know because these family members like to crow about it.

    I think it is disgusting. Big Pharma has infiltrated Hippocrates. :Retro mad:
     
  4. Otis

    Otis Señor Mumbler

    Messages:
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    USA
    Yes, the way the drug reps work their way right into the MDs mindset is shocking.

    I've got a pill for that. Side effects, I've got a pill for that too. Pretty soon who knows the side effects vs. symptoms. The is very true in older people and ME patients who are more sensitive to side effects.

    I admit I need meds to sleep, but I like the idea of saying "SHE helps me sleep". :)
     
  5. Otis

    Otis Señor Mumbler

    Messages:
    1,116
    Likes:
    116
    USA
    Yes, the way the drug reps work their way right into the MDs mindset is shocking.

    I've got a pill for that. Side effects, I've got a pill for that too. Pretty soon who knows the side effects vs. symptoms. The is very true in older people and ME patients who are more sensitive to side effects.

    I admit I need meds to sleep, but I like the idea of saying "SHE helps me sleep". :)
     

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