Parkinsons Dis. 2016; 2016: 6219249. Published online 2016 May 24. doi: 10.1155/2016/6219249 PMCID: PMC4894988 Essential Oils May Lead α-Synuclein towards Toxic Fibrils Formation Dina Morshedi * and Mahour Nasouti https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894988/ Biomed Res Int. 2014;2014:736385. doi: 10.1155/2014/736385. Epub 2014 Jan 12. Neurotoxicants are in the air: convergence of human, animal, and in vitro studies on the effects of air pollution on the brain. https://www.ncbi.nlm.nih.gov/pubmed/24524086 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912642/ Air pollution is a mixture comprised of several components, including ambient particulate matter (PM), gases, organic compounds, and metals. The association between air pollution and morbidity and mortality caused by respiratory and cardiovascular diseases is well established [1–3]. Among air pollution components, PM is believed to be the most widespread threat and has been heavily implicated in disease [2, 4, 5]. PM is broadly characterized by aerodynamic diameter (e.g., PM10 and PM2.5, equivalent to <10 μm and 2.5 μm in diameter, respectively; ). Ultrafine particulate matter (UFPM; <100 nm) is of much concern, as these particles can more easily enter the circulation and distribute to various organs, including the brain [6, 7]. Of most relevance is also the fact that UFPM can gain access to the brain directly through the nasal olfactory mucosa, reaching first the olfactory bulb [7–11]. In vitro studies have shown that PM is cytotoxic and that toxicity is size-dependent, with the smaller UFPM being better able to enter the cells and exert toxic effects [12–15]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912642/citedby/ I cant even be around essential oils, at all, amoung many other smelly things, when I went to Gray in Az. he actually had this lady, Kristina Townsend, trying to push essential oils on everyone that saw him, I tried telling her that wasn't the thing to do! she was a lady that was supposedly very ill from a water damaged building touting essential oils as a cure all, don't fall for it!