I just ran across the website [for the first time] for Envita Clinic in Scottsdale, Arizona. I thought the article at the following link provided one of the best and most succinct explanations and descriptions of ME/CFS I've ever run across. But just because they have a good understanding of it doesn't necessarily mean they have a good track record in treating it. Has anybody visited this clinic? Care to share your experiences? -- Thanks! Envita Clinic Here's the concluding paragraph in this particular article. Following this paragraph, they have a number of links to other articles; which I hope to read sometime soon. How did your Fibromyalgia and Chronic Fatigue Syndrome Start? The short answer: triggers. Another critical point is that fibromyalgia syndrome is initiated by a triggered physical trauma; a car accident, surgery, the death of a loved one or other psychological and emotional stressors. This is what we have also seen in several autoimmune diseases, chronic fatigue syndrome and especially Lyme disease. The infection is already present in the body the whole time, but it is usually the trigger that weakens the immune system. Then the body's defense system goes down, then Pandora's Box is opened and you start to see the full-blown disease expressed. The "trigger" phenomenon is often related to HPA (axis) system in the brain. The term chronic Lyme disease complex was developed by the doctors at Envita to explain to our patients that numerous bacterial (including Borrelia), viral, fungal, parasitic infections, and other tick-borne coinfections all bring about musculoskeletal pain, joint pain, neurological pain, digestive issues, hormonal problems, headaches, cognitive problems and the list goes on.