Fluge & Mella's pre-trial study highlights life-changing potential of rituximab
Sasha gives the background and Simon gives the interpretation of the latest study from Haukeland, published today...
Discuss the article on the Forums.

Endothelial nitric oxide increased in Normal Flow POTs

Discussion in 'Problems Standing: Orthostatic Intolerance; POTS' started by ramakentesh, Oct 25, 2011.

  1. ramakentesh

    ramakentesh Senior Member

    Messages:
    526
    Likes:
    84
    Hi this may be of interest, a subset of POTS patients that appear to have too much endothelial and neuronal nitric oxide resulting in blood pooling specific to the stomach region. This could potentially explain B12 efficacy in some forms of POTS/CFS as it is a potent scavenger and potential competitor of NO.

    http://ajpheart.physiology.org/content/301/3/H704.abstract

    Strange thing is, another major subset of POTS seems to have elevated angiotensin and REDUCED neuronal nitric oxide bioavailability.
     

See more popular forum discussions.

Share This Page