The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
Discuss the article on the Forums.

Elevated IgE

Discussion in 'Immunological' started by bleep123, Mar 31, 2016.

  1. bleep123

    bleep123

    Messages:
    2
    Likes:
    0
    Hi,

    I had my IgE levels checked recently and they were around 167 kU/L, which is high. I was wondering if anyone has had experience with this. I had a stool test for parasites and nothing was found (not CDSA). Also, white blood cell counts look sane, so no blood cancers. Any thoughts on which kind of doctor I should see? The doctor who performed the test is a functional doctor. I'm wondering if I should see a specialist, if so what kind?

    Thank you!
     
  2. CCC

    CCC Senior Member

    Messages:
    356
    Likes:
    453
    Stool test: which one did you get?

    Was it just the standard no-frills test, which will often come up negative? Or a PCR test for specific parasites? Or a test using fixative (also for specific parasites). We ended up (accidentally) doing a side-by-side test (i.e. all three tests on the same stool), and only the PCR test came up positive.

    We found this website to be of great help: http://www.badbugs.org/ (albeit a bit depressing from the years of misdiagnosis and then refusal to treat the poor person had to endure).

    We had a diagnosis, but the first treatment was ineffective. The Bad Bugs site led us to the CDD in Sydney (Australia). At the first appointment, the GI specialist looked down the long list of blood tests and results and could easily attribute a few of the results to parasites, IgE amongst them.
     
  3. bleep123

    bleep123

    Messages:
    2
    Likes:
    0
    It was the standard no-frills test that came back negative I believe. I took the CDSA as well and the results are pending.

    Did you eventually find effective treatment?
     
  4. JaimeS

    JaimeS Senior Member

    Messages:
    3,155
    Likes:
    11,563
    Mid-Ohio Valley, United States
    I have elevated IgE -- in the 300s. But no one has been able to discuss why it's so high. I had a sample done at RedLabs and it did find dysbiosis. However, despite abx use, my IgE is a little higher than it was in the past...

    Sorry that I have no answers for you.

    -J
     
    bleep123 likes this.
  5. Jonathan Edwards

    Jonathan Edwards "Gibberish"

    Messages:
    5,210
    Likes:
    31,614
    My understanding is that IgE levels in this sort of range probably mean nothing much. The person is statistically more likely to have allergy but if there are no signs of allergy it may mean nothing. A simple screen for parasites seems sensible. I think you have to make your own decision on whether or not to consult someone else if you are not happy with the interpretation of the clinician who ordered the test.
     
    bleep123 likes this.
  6. CCC

    CCC Senior Member

    Messages:
    356
    Likes:
    453
    We find out next week!

    FYI: Our IgE was up around 1300 for a long time. After the first round of antibiotics (10 days of doxycycline), we had a false negative stool test (quite common due to intermittent 'shedding').

    The CDD site includes a link to a report of a side-by-side comparison of plain stool test with a fixative one: http://www.cdd.com.au/pages/disease_info/parasites.html. It makes the point that a plain stool test never detects the parasite that was the subject of that paper.

    Your IgE is very low, though. We'd be happy to plummet to that level. I'd ignored the original number to some extent because Americans always seem to have slightly different units with different numbers of zeros after things
     
    bleep123 and JaimeS like this.
  7. CCC

    CCC Senior Member

    Messages:
    356
    Likes:
    453
    O happy day.

    The first test (a PCR test) came back negative.

    Next for the oh-so-messy and yukky test with fixative and many jars. This is the one the CDD GI specialist has asked for.
     
    JaimeS likes this.
  8. Tomas

    Tomas

    Messages:
    19
    Likes:
    3
    I have IgE of about 600. It used to around 1000-1200, but it almost halved after course of Quensyl. I still believe that IgE is in the root of my illness (low grade fevers).
     
  9. CCC

    CCC Senior Member

    Messages:
    356
    Likes:
    453
    600 is quite high.

    I see IgE as a sign rather than as a cause in our case.
     

See more popular forum discussions.

Share This Page