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Dysfunctional Endogenous Analgesia During Exercise in Patients with Chronic Pain: To Exercise or Not

Discussion in 'Latest ME/CFS Research' started by Dolphin, Jul 15, 2012.

  1. Dolphin Senior Member

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    Free full text: http://www.painphysicianjournal.com/2012/july/2012;15;ES205-ES213.pdf


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  2. biophile Places I'd rather be.

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    "But how?" Of course, GET and cognitive restructuring are presented as the answer. :cautious:
  3. mellster Marco

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    San Francisco
    I think one could try to combine anti inflammatories, lactic acid reducers with a general opiod stimulating therapy such as LDN to increase exercise tolerance.
  4. Battery Muncher Senior Member

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    Interesting thoughts, mellster. What works as a lactic acid reducer? Is it available over the counter? And what is LDN?
  5. Sam Carter Senior Member

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    LDN = low dose naltrexone (an opioid antagonist).
  6. Simon Senior Member

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    Monmouth, UK
    I've only read the absract, but some of the findings are interesting:
    So, for example, while exercise leads to pain killing effects in healthy individuals, it leads to the reverse in fibromyalgia. I think that's important. And the conclusion about avoiding exacerbating sypmptoms is certainly at odds with the PACE GET cavalier advice for dealing with setbacks ("Carry on!").
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  7. biophile Places I'd rather be.

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    If "exercise therapy should be individually tailored with emphasis on prevention of symptom flares", then many patients won't be doing any additional exercise at all then.
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