May 12, 2017 Is International ME/CFS and FM Awareness Day
International ME/CFS and FM Awareness Day is May 12th, 2017. Jody Smith shares some information about upcoming events and ways you can be heard ...
Discuss the article on the Forums.

Dupuytren’s Disease?

Discussion in 'Genetic Testing and SNPs' started by Methyl Health, Nov 3, 2014.

  1. Methyl Health

    Methyl Health

    Messages:
    43
    Likes:
    29
    Anyone here have it? Or ever have trouble with plantar fasciitis? Looking to compare some genes.
     
  2. brenda

    brenda Senior Member

    Messages:
    1,935
    Likes:
    1,463
    UK
    Hi yes l have it and fortunately not too advanced with only one nodule.
     
  3. Helen

    Helen Senior Member

    Messages:
    2,060
    Likes:
    3,177
    ... or "the Viking disease" as it is called in Sweden. Most frequent in Scandinavia compared to the world, and here there is an injection treatment that people witness is highly effective and a quick treatment so @brenda I hope this could help you too. Earlier you often noticed this disease when you shook hands with elderly men in my country but never nowadays, so the treatment seems to work. FWIW
     
  4. Methyl Health

    Methyl Health

    Messages:
    43
    Likes:
    29
    Same here, not too advanced. My grandmother's hand was curled tight. I am looking at your SNPs and I see some similarities.
    Seems to be associated with the Wnt Signalling Pathway as well
    http://www.ncbi.nlm.nih.gov/pubmed/21732829

    Wondering if you could look up your SNPs for these:
    FRZB - Rs7775 - (I am C,G)
    WNT2 - Rs4730775 - (I am T,T)
    WNT7B - Rs6519955 - (I am T,T)

    I think I am homozygous for all of these. For more on the Wnt pathway:
    https://www.mdc-berlin.de/8163894/e...12-keeping_the_right_balance_-_new_insights_i
     
  5. brenda

    brenda Senior Member

    Messages:
    1,935
    Likes:
    1,463
    UK
    FRZB - Rs7775 - (I am C,G) GG
    WNT2 - Rs4730775 - (I am T,T) CT
    WNT7B - Rs6519955 - (I am T,T) no call.

    Thanks for the link.
     
  6. ahmo

    ahmo Senior Member

    Messages:
    4,329
    Likes:
    6,508
    Northcoast NSW, Australia
    Mine began when I was about 40 yo. Maternal grandfather had it severely, possibly father, tho I'm unsure, one brother. After 14 years finger of one hand had 45 degree bend, both palms severely affected, small nodule under one foot. I went to Switzerland for needle treatment, which relieved the worst of it. A year later had another treatment. There was still significant residual contracture.

    9 years following this procedure I began GAPS diet. By the end of the second week gluten/dairy-free, I stepped away from my disbelief: all the remaining contractures had melted. My hands now would be unremarkable to anyone who didn't know , except for the deformed trigger finger I hadn't had treated in time, and remains crooked.

    FRZB: 288326 GG; 7775 CC
    WNT2 rs4730775(T;T) rs2896218(A;A)
    WNT7B none
     
  7. *GG*

    *GG* Senior Member

    Messages:
    6,112
    Likes:
    4,694
    Concord, NH
    Yes, have history of Plantar Fascitis, better in the past, but the few bike rides I did this summer aggravated it, and still feeling it some. Have not had much done in regards to genetic testing, so not going to be able to help in that regard.

    GG
     
  8. Valentijn

    Valentijn WE ARE KINA

    Messages:
    14,280
    Likes:
    45,787
    I had Plantar Fasciitis starting about 8 years ago. I don't have any problems with it currently because I don't stand or walk much ... maybe I should thank the ME for that :rolleyes: My mother also has it.

    I also have a big flat bump in the center of each foot near the heel, starting sometime in the past year or so. Maybe plantar fibromas or Plantar Fibromatosis.
     

See more popular forum discussions.

Share This Page