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Dry vitamine E = Tocopheryl succinate (TOS), warning

Discussion in 'Alternative Therapies' started by pattismith, Oct 28, 2017.

  1. pattismith

    pattismith Senior Member

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    I thought that Dry vitamine E will be both a succinate donor and a vitamine E donor, both interesting for ME...

    I was wrong!


    Alpha Tocopheryl Succinate in Cancer Care
    Just another Vitamin E?
    By Tina Kaczor, ND, FABNO

    Abstract
    dl-alpha tocopheryl succinate (aTOS) is an analogue of alpha-tocopherol (vitamin E) with unique biological properties. Unlike its parent compound, aTOS does not have a redox potential and is therefore not an antioxidant.
    Its ability to prolong cell cycle arrest, induce apoptosis, and act as a radiosensitizer make aTOS a compound of great interest in integrative cancer care. In vitro and in vivo evidence suggests it is capable of simultaneously protecting normal cells from chromosomal damage while potentiating cytotoxicity of conventional therapies. Application of aTOS to chemopreventative and cancer treatment strategies should take into account these known actions as well as conversion back to alpha tocopherol (aTOH) systemically.

    (full article available and very interesting)
     
  2. Learner1

    Learner1 Professional Patient

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    Pacific Northwest
    Interesting! However, I've not seen it used as one of the many integrative cancer treatments used in the naturopathic clinics staffed by doctors with relationships to the Bastyr Integrative Oncology Research Center, where my cancer was successfully treated with high dose vitamin C and glutathione.

    Also, I did a lot of research st the time and found that antioxidants like vitamin C during cancer treatment can potentiate the effectiveness of chemotherapy drugs while protecting the healthy cells.

    These links discuss more about aTOS. Apparently the succinate is there as the alpha tocopherol would be unstable without it in the bottle. It would seem that it gets broken off in the body at some point.

    http://www.ijporlonline.com/article/S0165-5876(16)30052-0/pdf

    http://www.drpasswater.com/nutrition_library/traber2.html

    https://www.google.com/url?q=http:/...kAcYQFggaMAU&usg=AOvVaw1pANB8lMl3BILUzSdm6SRb
     

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