I have not been up on the research of mitochondrial damage in general illness, and certainly not on this topic as it pertains to ME. Dr. Myhill has good info on her site, but I still have questions. If we consider mito dysfunction to be part of the ME spectrum of "malfunctions" , is it such that the mito DNA damage is that of an accelerated aging process? In other words, if we were able to address the healing of mitochondria and put ourselves in recovery in a simple manner, would there still be the effects of damage in the DNA? Or could this theoretically be rolled back also. I ask this because I am 24 years old, and I often feel like I am 70 or so. I do not have full blown ME, but I do struggle with faitigue quite a bit. i'm holding out hope for some sort of recovery/solution, but I fear that the damage done is to the core, at the genetic level. Anyone familiar open to helping me out here?