Dr Martin Pall On the Dangers of Increased Glyphosate

[liverock]

"A number of people with these diseases(ME,CFS,MCS,FM) have reported apparent
sensitivity to roundup herbicide and its "active" ingredient, glyphosate
and there has been concern because the EPA has apparently already
approved of allowing much higher levels of glyphosate in non-organic
foods.

I recently found a paper showing that glyphosate acts as a
toxicant by activating voltage-gated calcium channels, the same
mechanism activated by electromagnetic field exposure. There is no
reason to doubt that such increased intracellular calcium levels should
be able to up-regulate the NO/ONOO- cycle and therefore most if not all
NO/ONOO- cycle caused diseases.

I think that there is reason for concern here. It may well be the case that glyphosate may act synergistically with EMF exposures to together produce much higher
pathophysiological responses. You are welcome to freely forward this
message."
Martin Pall

Free Radic Biol Med. 2013 Dec;65:335-46. doi:
10.1016/j.freeradbiomed.2013.06.043. Epub 2013 Jun 29.

http://www.ncbi.nlm.nih.gov/pubmed/23820267

Roundup disrupts male reproductive functions by triggering
calcium-mediated cell death in rat testis and Sertoli cells.

de Liz Oliveira Cavalli VL, Cattani D, Heinz Rieg CE, Pierozan P,
Zanatta L, Benedetti Parisotto E, Wilhelm Filho D, Mena Barreto Silva
FR, Pessoa-Pureur R, Zamoner A.

Abstract

Glyphosate is the primary active constituent of the commercial pesticide
Roundup. The present results show that acute Roundup exposure at low
doses (36 ppm, 0.036 g/L) for 30 min induces oxidative stress and
activates multiple stress-response pathways leading to Sertoli cell
death in prepubertal rat testis. The pesticide increased intracellular
Ca(2+) concentration by opening L-type voltage-dependent Ca(2+) channels
as well as endoplasmic reticulum IP3 and ryanodine receptors, leading to
Ca(2+) overload within the cells, which set off oxidative stress and
necrotic cell death. Similarly, 30 min incubation of testis with
glyphosate alone (36 ppm) also increased (45)Ca(2+) uptake. These events
were prevented by the antioxidants Trolox and ascorbic acid. Activated
protein kinase C, phosphatidylinositol 3-kinase, and the
mitogen-activated protein kinases such as ERK1/2 and p38MAPK play a role
in eliciting Ca(2+) influx and cell death. Roundup decreased the levels
of reduced glutathione (GSH) and increased the amounts of thiobarbituric
acid-reactive species (TBARS) and protein carbonyls. Also, exposure to
glyphosate-Roundup stimulated the activity of glutathione peroxidase,
glutathione reductase, glutathione S-transferase, γ-glutamyltransferase,
catalase, superoxide dismutase, and glucose-6-phosphate dehydrogenase,
supporting downregulated GSH levels. Glyphosate has been described as an
endocrine disruptor affecting the male reproductive system; however, the
molecular basis of its toxicity remains to be clarified. We propose that
Roundup toxicity, implicated in Ca(2+) overload, cell signaling
misregulation, stress response of the endoplasmic reticulum, and/or
depleted antioxidant defenses, could contribute to Sertoli cell
disruption in spermatogenesis that could have an impact on male fertility.

In other words increased glyphostate will make our symptoms worse whilst Smart meters, mobile and cordless phones, will add to the problem whilst making men infertile.

 

[Forebearance]

Thank you for sharing that!

 

[liverock]

DRAMATIC INCREASE IN KIDNEY DISEASE IN COUNTRIES USING ROUNDUP (GLYPHOSATE)

Reports of kidney disease deaths have been made in countries using ROUNDUP (Glyphosate} weedkiller for several years and now data is showing that kidney deaths have doubled in the US since the introduction of GM foods.

http://www.greenmedinfo.com/blog/dr...s-and-abroad-linked-roundup-glyphosate?page=1

A series of graphs based on data from the USDA, National Cancer Institutes, Centers for Disease Control, have recently surfaced, depicting a steep rise in the rates of kidney disease in the US from the time of the introduction of glyphosate and GM food, reveals that the US may also be suffering from an epidemic of glyphosate-linked kidney damage.