This is a copy of a thread from another site where Dr Mariano asnwers a patients question on adrenal fatigue and talks about his general field of practice where he tries to blend psychology, psychiatry, neurology, endocrinology, immunology, metabolism, and nutrition together. Dear Doctor, Do you think that people who have hypothyroidism since many year's recover from adrenal fatigue ? I think it's impossible. When I begin HC, I feel little better and sometimes when I forget my HC caps for one day I don't feel bad t all. Sometimes, when I wake up the morning I feel OK depiste I forget my HC caps. At this times, 7 year's on HC, I don't feel well when I wake up. I need to wait 45 mn after my cortisol dose to feel good. I I forget my HC dose I feel bad. My adrenal fatigue is more severe than before. What wrong with this treatment, because Jefferies saidthat low dose HC doesn't lower your internal production but help to heal adrenal. I disagree with Dr Wilson about adrenal fatigue. I known many people like me that don't recover from this " adrenal fatigue", may be it's a real adrenal insufficiency.