Hey Alex, If Cort's case pans out as the trend rather than the exception, that would imply that the higher-functioning individuals have more antibodies. I don't think the history of this disease has shown things to be as simple as you describe. What seems more likely is that we have excess inflammation along with immune deficiencies. NK cells are low, whereas certain cytokines are high. The CD4/CD8 ratio is the mirror of AIDS. Neutrophils are in the basement, and Rnase-L enzyme activity is through the roof.