These experiments are proving to be a fruitless endeavour thus far. I've tried many of the Goldstein meds that are on his decision tree. But without access to certain drugs and certain profiling drugs, I fear that finding the magic bullet(s) will be like a needle in a haystack. Perhaps Dr. Goldstein is correct that many patients can try 100 drugs without any benefit and reach the endpoint of feeling dramatically better on drug 101. But those folks were lucky to have his guidance along the way. Perhaps he is also correct that he had special "tricks of the trade" that only he knew and no one else was interested in learning. (See page xiii of the Foreword to Tuning The Brain). On the bright side though I guess we're at least lucky to have the books as a guide which is better than nothing I suppose.