1. Patients launch $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
Can You Come for a Visit? My ME/CFS Says No
My daughter and son-in-law just had a baby last week. We are thrilled. But we won't be able to see the baby or hold her any time soon. We won't be able to take over little gifts or help out with housework or babysitting.
Discuss the article on the Forums.

Doxepin - Is it a good choice for first-ever sleep aid (for deep sleep)?

Discussion in 'General Treatment' started by Carola, Jul 30, 2011.

  1. Carola

    Carola

    Messages:
    30
    Likes:
    6
    I've never taken a sleeping pill in my life, but after waking up tired for the last year and a half, I'm ready for some help. I don't need help falling asleep but would love to get some sort of restorative sleep. I've read that low-dose Doxepin may be helpful and would appreciate any advice about this.

    I'm also on antihistamines 24/7 (for chronic idopathic uritcaria), and so I need to think about interactions. And, if age is a factor - I'm 65. Thanks for any input!
  2. LaurelW

    LaurelW Senior Member

    Messages:
    552
    Likes:
    92
    Utah
    This worked really well for me some years ago, but it made me gain so much weight I had to give it up. I tried it again last year, and it didn't really work, and I gained 10 pounds in 2 weeks that I have yet to shed.
  3. Otis

    Otis SeƱor Mumbler

    Messages:
    1,116
    Likes:
    116
    USA
    Doxepin has antihistamine properties which is probably one reason it helps with sleep. That may or may not be a good thing in your case. I took it years back and it helped me sleep some but I found that I needed a dose that was high enough that it resulted in a hangover. I had no way to measure it at the time - now I have a Zeo which helps me monitor my sleep and I've learned that my impressions are borne out by the Zeo measurements.

    I think it's a reasonable first step for tacking sleep. Many people (esp. ME patients) get too drugged by the smallest tablet/capsure size (10mg) so you might want to look into the elixer. Here' a thread you might want to check out.

    Best of luck.
  4. TheMoonIsBlue

    TheMoonIsBlue Senior Member

    Messages:
    442
    Likes:
    54
    Hi LaurelW,

    I keep reading about the weight gain issue with Doxepin. I wonder if it is dose dependant. How many milligrams were you taking? I wonder why weight gain is such an issue for so many with this med, if the doses used are very low......maybe it is just something with all trycyclics?
  5. Carola

    Carola

    Messages:
    30
    Likes:
    6
    Thank you all for this very helpful information. Interesting about the antihistamine properties of the drug as well as the weight-gain issue. Over the last 15 years, I've built up quite a tolerance for antihistamines. So, I'm not sure if a sleep aid that relies at least in part on antihistamine properties is a good choice for me or not.

    As it happens, the antihistamine I rely on, ketotifen fumerate, is also associated with weight gain. So I feel somewhat cautious about adding another drug with that association, especially since I can't exercise any more.

    Again, thanks! Much to ponder.
  6. heapsreal

    heapsreal iherb 10% discount code OPA989,

    Messages:
    7,150
    Likes:
    4,408
    australia (brisbane)
    great for sleep but can make u feel groogy the next day so try it when u having nothing planned the next day. I also put weight on with this meds when used nightly but using it every so often helped me avoid weight gain.

    cheers!!!
  7. LaurelW

    LaurelW Senior Member

    Messages:
    552
    Likes:
    92
    Utah
    I was on 30 mg., but never tried lower, so don't know what would happen there.
  8. ggingues

    ggingues $10 gift code at iHerb GAS343 of $40

    Messages:
    3,953
    Likes:
    805
    Concord, NH
    Doxepin did not work for me, but I take Mirtazapine, started at 15mgs or so, now up to 30mg/night. I also use a VPAP with oxygen, and I feel much better when I wake in the morning now, I also wake up later, later work start time. I also take 3mgs of Melatonin and LDN, and just went up to 6mgs/ of Tinzanidine.

    GG
  9. Carola

    Carola

    Messages:
    30
    Likes:
    6
    Thanks for the feedback on doxepin and details on other possibilities - very helpful.
  10. grant107

    grant107 Jean

    Messages:
    92
    Likes:
    0
    Ormond Beach, Fl
    I have taken .5mg of Doxepin for several years. It helps my sleep but any higher dose and i have a hangover.

See more popular forum discussions.

Share This Page