I am male, 39 and have been trying to get some kind of diagnosis for the past 10 years for unexplained symptoms. I obviously have some kind of histamine disorder. Does this sound like MCAD? I have no rashes or unusual pigmentation. NasalCrom helps with sinus symptoms so I am planning a trial run of ketotifen. - Insomnia (severe) - Fatigue - Burning mouth, gums, eyes and sinuses - Sinus congestion and irritation (worse in the early AM, especially during weather changes) - Acid reflux (taking famotidine) - Random nausea - Trouble swallowing - Frequent headache - Sensitive to meds and supplements (B vitamins provoke anxiety) - Poor exercise tolerance (had to give up weight lifting; makes me wired and tired) 12/09 Histamine, Plasma 1.95 ng/mL <1.00 ALERT 06/12 Tryptase 7.0 ug/L 2.2-13.2 NORMAL 07/13 Histamine, Whole Blood 151 ng/mL 12-127 HIGH Celiac & IGE food allergies: NORMAL IGG food allergies: dairy,wheat,egg (not sure if meaningful) Lyme: one western blot came back IGM positive (false positive?) Thanks for any replies or advice.