The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
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Does Low Dose Naltrexone (LDN) reduce inflammation?

Discussion in 'Pain and Inflammation' started by ebethc, Oct 21, 2014.

  1. ebethc

    ebethc Senior Member

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    Hi - does anyone know if LDN reduces inflammation? It does a good job on pain, not sure beyond that, though.

    thanks
     
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  2. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    @ebethc
    Many report that it does, but I don't have documentation handy.

    Sushi
     
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  3. ahmo

    ahmo Senior Member

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    You can check these sites, there might be further info:
    http://www.lowdosenaltrexone.org/index.htm

    https://sites.google.com/site/dudleyslowdosenaltrexonesites/
     
    NK17, filfla4, ebethc and 1 other person like this.
  4. Hip

    Hip Senior Member

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    LDN may reduce microglial activation, which is a central part of brain inflammation.
     
    ebethc likes this.
  5. ebethc

    ebethc Senior Member

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    @Sushi @ahmo @Hip

    I took TONS of vegetarian DHA yesterday and it made a dramatic (positive) effect on inflammation! Sinuses, throat, lungs all feel so much better, plus aches & pains. For some reason, the vegetarian (algae-sourced) DHA is much better for me than the fish-sourced DHA... I've been really sick all month after going on a gene protocol that included Arginine in early september... the arginine made my EBV flair..

    I took some leftover LDN 2 days ago and it really made my symptoms flare... It worked okay for me in the past, and I thought I'd try it again now that I've given up dairy & gluten. My body really didn't go for it this time around...
     
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  6. fibrodude84

    fibrodude84 Senior Member

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    LDN has shown in small trials to potentially reduce inflammation in inflammatory bowel disease (crohns and colitis)
     
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  7. nomad

    nomad Anyone interested in a London Support group?

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    I would be very keen to try this if its possible to get a private prescription for it. Anyone ?

    I have CFS, along with painful cramped muscles, and severe anxiety which leads me to suspect inflammation, particularly brain inflammation.
     
  8. CantThink

    CantThink Senior Member

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    Could it have been a herxheimer reaction? Every time I increased (or initially took) LDN I'd get a 5-7 day herxheimer before I saw improvement. It was quite scary the first time. I got used to it and although I found it unpleasant, I found it okay to deal with if I knew I'd see improvement afterwards.
     
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  9. CantThink

    CantThink Senior Member

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    bertiedog and nomad like this.
  10. nomad

    nomad Anyone interested in a London Support group?

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    Thanks @CantThink I hope they can prescribe without me still not having a definete diagnosis
     
  11. CantThink

    CantThink Senior Member

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    If they don't, you can get it from abroad with no prescription. You can buy the 50mg tablets - look up 'Preparing LDN at home' on Google.
     
  12. Ema

    Ema Senior Member

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    You can even get it now from IAS in 4.5 mg strength if you don't want to mess with dilution.
     
  13. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    I now get the 50 mg generic tablets from my local pharmacy (prescription required). It is very cheap and very easy to dilute--50 mgs in 50 mls: 1 ml = mg.

    Sushi
     
  14. ebethc

    ebethc Senior Member

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    What is IAS?

    thanks
     
  15. heapsreal

    heapsreal iherb 10% discount code OPA989,

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  16. Ema

    Ema Senior Member

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  17. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    It is really expensive at those 2 sources :(--I guess it is the trade-off for not requiring a script.
     
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  18. Dufresne

    Dufresne almost there...

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    Does anyone know where I can buy brandname Revia without a prescription at an affordable price?
     
  19. knackers323

    knackers323 Senior Member

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    Does LDN tend to improve fatigue levels?
     
  20. Ema

    Ema Senior Member

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    I guess I need to shop around...both of those sources are cheaper than my local compounding pharmacy with a script.

    Where do you get yours, @Sushi?

    ETA: Sorry, Sushi, missed your post above.
     

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