In this blog post, the poster describes his wife as having both CFS and hemochromatosis: http://cobbsblog.com/blog/?p=770 I had never heard of hemochromatosis, in which the body stores excess iron, but was startled to learn that it presents with one of my weirder symptoms, a bronze-colored hyperpigmentation of the skin (mine is on the sides of my forehead and cheekbones). This pigmentation appeared shortly *before* my sudden-onset CFS. (And has always been brushed off by doctors, including this classic line: "It doesn't look bad!" As if I'm solely concerned for vanity's sake.) Does anyone else have anything like this? Hemochromatosis is generally a genetic disorder. But then, the same is true for Neimann Pick C, the condition of the "childhood alzheimer's" twins who are XMRV+. I'm starting to wonder if XMRV is triggering epigenetic changes causing these conditions, previously latent, to start manifesting - ???