I've essentially been trying to treat this on my own. I just feel this is not something most doctors would take seriously. I've never mentioned the terms ME/CFS directly but I've essentially been complaining about EXTREME fatigue. So far outside of my other treatment it's only led to me seeing an psychiatrist and being put on anti-depressants(which didn't work, no surprise there). However, my psychiatrist have commented on CFS not being clearly defined and probably not real when talking about my fatigue in passing. With that said, I've been dealing with a chronic pain issue which fatigue/depression would be obvious co-morbidities. I've been able to manage my pain with cortisone/trigger point injections + pain meds. But the fatigue just got worse and worse. There's been times where I haven't left the house in 4-5days. Earlier on I was able to be somewhat productive with the use of coffee/diet soda + daily modafinil/armodafinil use. But now not even those work. They just end up compromising my ability to think clearly. Right now I'm working on getting my inflammation way down through diet + supplements. I've also resorted to making my own injectables (i.e L-carnitine, L-carnosine, Alcar, etc). Pharmceutical meds just really messes up my mind. I took pramipexole + ambien before for insomnia+rls and I felt like I was starting to go crazy. And of course it didn't have a significant impact to warrant its continued use. So I'm going to just keep trying to figure things out on my own until I can find a professional that's open-minded enough to help. Money, insurance, etc being barriers to finding and getting further professional treatment. Edit: Intranasal insulin something I just started as well. I'm hoping this will help with the brain fog at least.