Julie Rehmeyer's 'Through the Shadowlands'
Writer Never Give Up talks about Julie Rehmeyer's new book "Through the Shadowlands: A Science Writer's Odyssey into an Illness Science Doesn't Understand" and shares an interview with Julie ...
Discuss the article on the Forums.

Does anyone care for comparing MAO-A SNPs?

Discussion in 'Genetic Testing and SNPs' started by Gondwanaland, Apr 7, 2015.

  1. Gondwanaland

    Gondwanaland Senior Member

    Messages:
    4,719
    Likes:
    3,703
    With so many versions differing from my husband's I hope I am not the only one from us two who ended up with the wrong base.

    SNP versions me -- DH
    rs72382423 II -- I
    rs5906883 A or C CC -- A
    rs1465108 A or G GG -- A
    rs72373490 II I
    rs909525 C or T TT -- C
    rs3027397 A or G GG -- A
    rs2283724 A or G AA -- G
    rs2179098 A or G GG -- G
    rs1800464 A or C AA -- A
    rs1800659 A or G AA -- G
    rs58524323 A or G GG -- G
    rs6323 G or T TT -- G
    rs1799835 G or T TT -- T
    rs3027399 C or G GG -- G
    rs2235186 A or G GG -- A
    rs2235185 A or G GG -- A
    rs2072743 C or T CC -- T
    i5900065 G or T GG -- G
    rs979605 A or G GG -- A
    rs5905418 A or G AA -- A
    rs1803986 G or T GG -- G
    rs1137070 C or T CC -- T
    rs1800466 A or G AA -- A
    rs3027407 A or G GG -- A

    Anyway, I decided to try a low tyramine diet :grumpy:

    EDIT -- Click here for seeing your own MAOA SNPs.
    Edit 2 -- For reference the SNP reported by Genetic Genie and Sterling is MAO-A rs6323, being the G alelle (-/-) accounted for faster degradation of serotonin, dopamine, epineprine, and norepinephrine.
     
    Last edited: Apr 8, 2015
  2. drob31

    drob31 Senior Member

    Messages:
    1,273
    Likes:
    745
    MAOA 43516479 rs72382423
    I

    MAOA 43526943 rs5906883 A or C
    C

    MAOA 43538209 rs1465108 A or G
    G

    MAOA 43551260 rs72373490
    I

    MAOA 43553202 rs909525 C or T
    T

    MAOA 43557081 rs3027397 A or G
    G

    MAOA 43559576 rs2283724 A or G
    A

    MAOA 43565635 rs2179098 A or G
    G

    MAOA 43571197 rs1800464 A or C
    A

    MAOA 43574169 rs1800659 A or G
    A

    MAOA 43587431 rs58524323 A or G
    G

    MAOA 43591036 rs6323 G or T
    T

    MAOA 43591085 rs1799835 G or T
    T

    MAOA 43592722 rs3027399 C or G
    G

    MAOA 43595428 rs2235186 A or G
    G

    MAOA 43595743 rs2235185 A or G
    G

    MAOA 43599521 rs2072743 C or T
    C

    MAOA 43599964 i5900065 G or T
    G

    MAOA 43601363 rs979605 A or G
    G

    MAOA 43602965 rs5905418 A or G
    A

    MAOA 43603113 rs1803986 G or T
    G

    MAOA 43603391 rs1137070 C or T
    C

    MAOA 43603735 rs1800466 A or G
    A

    MAOA 43604841 rs3027407 A or G
    no call

     
    Gondwanaland likes this.
  3. ahmo

    ahmo Senior Member

    Messages:
    4,382
    Likes:
    6,641
    Northcoast NSW, Australia
    Please...tell me you can make something meaningful from this...48 of them... [​IMG]

    So what's the difference between low tyramine and low histamine??

    MAOA 43516479 rs72382423 II
    MAOA 43517364 rs3788862 A or G GG
    MAOA 43518188 rs5905702 G or T GG
    MAOA 43519176 rs6520893 A or G AA
    MAOA 43526548 rs6520894 G or T TT
    MAOA 43526943 rs5906883 A or C CC
    MAOA 43527624 rs5906893 C or T TT
    MAOA 43535927 rs7882699 A or G GG
    MAOA 43538209 rs1465108 A or G GG
    MAOA 43540295 rs5906938 A or G GG
    MAOA 43544506 rs12688067 C or T TT
    MAOA 43547310 rs5906957 A or G GG
    MAOA 43551260 rs72373490 II
    MAOA 43552477 i5900171 A or C CC
    MAOA 43553202 rs909525 C or T TT
    MAOA 43554672 rs3027396 C or T TT
    MAOA 43555564 rs6520897 A or C CC
    MAOA 43557081 rs3027397 A or G GG
    MAOA 43559576 rs2283724 A or G AA
    MAOA 43559976 rs2283725 A or G GG
    MAOA 43560273 rs2283726 A or G AA
    MAOA 43565635 rs2179098 A or G GG
    MAOA 43567173 rs28375424 C or T CC
    MAOA 43568861 rs9330645 A or G GG
    MAOA 43570824 rs12833929 A or G GG
    MAOA 43571197 rs1800464 A or C AA
    MAOA 43573666 rs12843268 A or G GG
    MAOA 43574169 rs1800659 A or G AA
    MAOA 43575061 rs28439389 A or G GG
    MAOA 43580860 rs28556796 A or G GG
    MAOA 43587431 rs58524323 A or G GG
    MAOA 43587868 rs3810709 C or T TT
    MAOA 43588010 rs6610845 C or T TT
    MAOA 43591036 rs6323 G or T TT
    MAOA 43591085 rs1799835 G or T TT
    MAOA 43592016 rs1800465 A or T AA
    MAOA 43592763 rs3027400 G or T GG
    MAOA 43593479 rs12689575 A or G GG
    MAOA 43595428 rs2235186 A or G GG
    MAOA 43595678 rs3027403 C or T CC
    MAOA 43599521 rs2072743 C or T CC
    MAOA 43599964 i5900065 G or T GG
    MAOA 43599982 rs7065428 A or G AA
    MAOA 43601363 rs979605 A or G GG
    MAOA 43603113 rs1803986 G or T GG
    MAOA 43603391 rs1137070 C or T CC
    MAOA 43603735 rs1800466 A or G AA
    MAOA 43604841 rs3027407 A or G GG
     
    Gondwanaland likes this.
  4. PeterPositive

    PeterPositive Senior Member

    Messages:
    1,426
    Likes:
    1,035
    It's easier for me to paste from the raw data, the html table results badly formatted here.
    Does this help?

    Code:
    rs72382423  X   43516479    I
    rs3788862   X   43517364    G
    rs5905702   X   43518188    G
    rs6520893   X   43519176    A
    rs6520894   X   43526548    T
    rs5906883   X   43526943    C
    rs5906893   X   43527624    T
    rs7882699   X   43535927    G
    rs1465108   X   43538209    G
    rs5906938   X   43540295    G
    rs12688067  X   43544506    T
    rs5906957   X   43547310    G
    rs72373490  X   43551260    I
    i5900171    X   43552477    C
    rs909525    X   43553202    T
    rs3027396   X   43554672    T
    rs6520897   X   43555564    C
    rs3027397   X   43557081    G
    rs2283724   X   43559576    A
    rs2283725   X   43559976    G
    rs2283726   X   43560273    A
    rs2179098   X   43565635    G
    rs28375424  X   43567173    C
    rs9330645   X   43568861    G
    rs12833929  X   43570824    G
    rs1800464   X   43571197    A
    rs12843268  X   43573666    G
    rs1800659   X   43574169    A
    rs28439389  X   43575061    G
    rs28556796  X   43580860    G
    rs58524323  X   43587431    G
    rs3810709   X   43587868    T
    rs6610845   X   43588010    T
    rs6323  X   43591036    T
    rs1799835   X   43591085    T
    rs1800465   X   43592016    A
    rs3027400   X   43592763    G
    rs12689575  X   43593479    G
    rs2235186   X   43595428    G
    rs3027403   X   43595678    --
    rs2072743   X   43599521    C
    i5900065    X   43599964    G
    rs7065428   X   43599982    A
    rs979605    X   43601363    G
    rs1803986   X   43603113    G
    rs1137070   X   43603391    C
    rs1800466   X   43603735    A
    rs3027407   X   43604841    --
     
    Gondwanaland likes this.
  5. pogoman

    pogoman Senior Member

    Messages:
    188
    Likes:
    173
    43516479 rs72382423
    I
    43526943 rs5906883 A or C
    A
    43538209 rs1465108 A or G
    A
    43551260 rs72373490
    I
    43553202 rs909525 C or T
    C
    43557081 rs3027397 A or G
    A
    43559576 rs2283724 A or G
    G
    43565635 rs2179098 A or G
    G
    43571197 rs1800464 A or C
    A
    43574169 rs1800659 A or G
    G
    43587431 rs58524323 A or G
    G
    43591036 rs6323 G or T
    G
    43591085 rs1799835 G or T
    T
    43592722 rs3027399 C or G
    G
    43595428 rs2235186 A or G
    A
    43595743 rs2235185 A or G
    A
    43599521 rs2072743 C or T
    T
    43599964 i5900065 G or T
    G
    43601363 rs979605 A or G
    A
    43602965 rs5905418 A or G
    A
    43603113 rs1803986 G or T
    G
    43603391 rs1137070 C or T
    T
    43603735 rs1800466 A or G
    A
    43604841 rs3027407 A or G
    A
     
    Gondwanaland likes this.
  6. ebethc

    ebethc Senior Member

    Messages:
    1,275
    Likes:
    861
    @Gondwanaland - here are my results...

    What's the diff between MAO-a vs. MAO-b?

    Didn't you say quercetin is a MAO inhibitor? is that a good thing or a bad thing?
     

    Attached Files:

  7. Gondwanaland

    Gondwanaland Senior Member

    Messages:
    4,719
    Likes:
    3,703
    Thanks, folks, I have been compiling a spreadsheet, but the fact that some people have double as much os SNPs tested by 23andMe is making this too much work.
    [​IMG]
    From: http://www.cnsspectrums.com/aspx/articledetail.aspx?articleid=1791

    From: http://en.wikipedia.org/wiki/Monoamine_oxidase
    *** here is why vit B2 supplementation is recommended (as per @Sherpa ). I think I didn't tolerate it in the past because I had a downregulation in serotonin production (see below).

    It is a good thing if it makes you feel better, and a bad thing if it makes you feel worse ;)

    In my understanding there are 2 main situations involved here:
    • the serotonin you produce is too much for your enzymes to break down and you get serotonin syndrome symptoms such as anxiety, breathlessness etc
    • this leads to a down regulation in the serotonin production, and you end up with too little serotonin and depression symptoms
    I have been reading with interest Ray Peat's ideas about serotonin being a poison :eek:
     
    ebethc likes this.
  8. ebethc

    ebethc Senior Member

    Messages:
    1,275
    Likes:
    861
    thanks. Quercetin really helps me (MAO inhibitor - though not sure if it's MAO a or b or both). Not sure if I have too much or too little, because I have terrible brain fog (too little? hard to say because brain fog can be caused by SO many things) and I do get too anxious.... When I was reading about genetics a lot, I felt that there was some difficulty breaking things down... (ie, neurotransmitters & estrogen, as I recall... but I don't remember which snp/snps)
     
  9. Gondwanaland

    Gondwanaland Senior Member

    Messages:
    4,719
    Likes:
    3,703
    @ebethc I find it difficult to figure out too!
     
    ebethc likes this.

See more popular forum discussions.

Share This Page