New Atmosphere, New Vision: Gibson and Whittemore Kick Off Invest in ME Conference 2016
Mark Berry reports on Dr. Gibson's introduction and Dr. Whittemore's keynote speech, at the 11th Invest in ME International ME Conference in London.
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Does anyone care for comparing MAO-A SNPs?

Discussion in 'Genetic Testing and SNPs' started by Gondwanaland, Apr 7, 2015.

  1. Gondwanaland

    Gondwanaland Senior Member

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    With so many versions differing from my husband's I hope I am not the only one from us two who ended up with the wrong base.

    SNP versions me -- DH
    rs72382423 II -- I
    rs5906883 A or C CC -- A
    rs1465108 A or G GG -- A
    rs72373490 II I
    rs909525 C or T TT -- C
    rs3027397 A or G GG -- A
    rs2283724 A or G AA -- G
    rs2179098 A or G GG -- G
    rs1800464 A or C AA -- A
    rs1800659 A or G AA -- G
    rs58524323 A or G GG -- G
    rs6323 G or T TT -- G
    rs1799835 G or T TT -- T
    rs3027399 C or G GG -- G
    rs2235186 A or G GG -- A
    rs2235185 A or G GG -- A
    rs2072743 C or T CC -- T
    i5900065 G or T GG -- G
    rs979605 A or G GG -- A
    rs5905418 A or G AA -- A
    rs1803986 G or T GG -- G
    rs1137070 C or T CC -- T
    rs1800466 A or G AA -- A
    rs3027407 A or G GG -- A

    Anyway, I decided to try a low tyramine diet :grumpy:

    EDIT -- Click here for seeing your own MAOA SNPs.
    Edit 2 -- For reference the SNP reported by Genetic Genie and Sterling is MAO-A rs6323, being the G alelle (-/-) accounted for faster degradation of serotonin, dopamine, epineprine, and norepinephrine.
     
    Last edited: Apr 8, 2015
  2. drob31

    drob31 Senior Member

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    MAOA 43516479 rs72382423
    I

    MAOA 43526943 rs5906883 A or C
    C

    MAOA 43538209 rs1465108 A or G
    G

    MAOA 43551260 rs72373490
    I

    MAOA 43553202 rs909525 C or T
    T

    MAOA 43557081 rs3027397 A or G
    G

    MAOA 43559576 rs2283724 A or G
    A

    MAOA 43565635 rs2179098 A or G
    G

    MAOA 43571197 rs1800464 A or C
    A

    MAOA 43574169 rs1800659 A or G
    A

    MAOA 43587431 rs58524323 A or G
    G

    MAOA 43591036 rs6323 G or T
    T

    MAOA 43591085 rs1799835 G or T
    T

    MAOA 43592722 rs3027399 C or G
    G

    MAOA 43595428 rs2235186 A or G
    G

    MAOA 43595743 rs2235185 A or G
    G

    MAOA 43599521 rs2072743 C or T
    C

    MAOA 43599964 i5900065 G or T
    G

    MAOA 43601363 rs979605 A or G
    G

    MAOA 43602965 rs5905418 A or G
    A

    MAOA 43603113 rs1803986 G or T
    G

    MAOA 43603391 rs1137070 C or T
    C

    MAOA 43603735 rs1800466 A or G
    A

    MAOA 43604841 rs3027407 A or G
    no call

     
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  3. ahmo

    ahmo Senior Member

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    Northcoast NSW, Australia
    Please...tell me you can make something meaningful from this...48 of them... [​IMG]

    So what's the difference between low tyramine and low histamine??

    MAOA 43516479 rs72382423 II
    MAOA 43517364 rs3788862 A or G GG
    MAOA 43518188 rs5905702 G or T GG
    MAOA 43519176 rs6520893 A or G AA
    MAOA 43526548 rs6520894 G or T TT
    MAOA 43526943 rs5906883 A or C CC
    MAOA 43527624 rs5906893 C or T TT
    MAOA 43535927 rs7882699 A or G GG
    MAOA 43538209 rs1465108 A or G GG
    MAOA 43540295 rs5906938 A or G GG
    MAOA 43544506 rs12688067 C or T TT
    MAOA 43547310 rs5906957 A or G GG
    MAOA 43551260 rs72373490 II
    MAOA 43552477 i5900171 A or C CC
    MAOA 43553202 rs909525 C or T TT
    MAOA 43554672 rs3027396 C or T TT
    MAOA 43555564 rs6520897 A or C CC
    MAOA 43557081 rs3027397 A or G GG
    MAOA 43559576 rs2283724 A or G AA
    MAOA 43559976 rs2283725 A or G GG
    MAOA 43560273 rs2283726 A or G AA
    MAOA 43565635 rs2179098 A or G GG
    MAOA 43567173 rs28375424 C or T CC
    MAOA 43568861 rs9330645 A or G GG
    MAOA 43570824 rs12833929 A or G GG
    MAOA 43571197 rs1800464 A or C AA
    MAOA 43573666 rs12843268 A or G GG
    MAOA 43574169 rs1800659 A or G AA
    MAOA 43575061 rs28439389 A or G GG
    MAOA 43580860 rs28556796 A or G GG
    MAOA 43587431 rs58524323 A or G GG
    MAOA 43587868 rs3810709 C or T TT
    MAOA 43588010 rs6610845 C or T TT
    MAOA 43591036 rs6323 G or T TT
    MAOA 43591085 rs1799835 G or T TT
    MAOA 43592016 rs1800465 A or T AA
    MAOA 43592763 rs3027400 G or T GG
    MAOA 43593479 rs12689575 A or G GG
    MAOA 43595428 rs2235186 A or G GG
    MAOA 43595678 rs3027403 C or T CC
    MAOA 43599521 rs2072743 C or T CC
    MAOA 43599964 i5900065 G or T GG
    MAOA 43599982 rs7065428 A or G AA
    MAOA 43601363 rs979605 A or G GG
    MAOA 43603113 rs1803986 G or T GG
    MAOA 43603391 rs1137070 C or T CC
    MAOA 43603735 rs1800466 A or G AA
    MAOA 43604841 rs3027407 A or G GG
     
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  4. PeterPositive

    PeterPositive Senior Member

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    It's easier for me to paste from the raw data, the html table results badly formatted here.
    Does this help?

    Code:
    rs72382423  X   43516479    I
    rs3788862   X   43517364    G
    rs5905702   X   43518188    G
    rs6520893   X   43519176    A
    rs6520894   X   43526548    T
    rs5906883   X   43526943    C
    rs5906893   X   43527624    T
    rs7882699   X   43535927    G
    rs1465108   X   43538209    G
    rs5906938   X   43540295    G
    rs12688067  X   43544506    T
    rs5906957   X   43547310    G
    rs72373490  X   43551260    I
    i5900171    X   43552477    C
    rs909525    X   43553202    T
    rs3027396   X   43554672    T
    rs6520897   X   43555564    C
    rs3027397   X   43557081    G
    rs2283724   X   43559576    A
    rs2283725   X   43559976    G
    rs2283726   X   43560273    A
    rs2179098   X   43565635    G
    rs28375424  X   43567173    C
    rs9330645   X   43568861    G
    rs12833929  X   43570824    G
    rs1800464   X   43571197    A
    rs12843268  X   43573666    G
    rs1800659   X   43574169    A
    rs28439389  X   43575061    G
    rs28556796  X   43580860    G
    rs58524323  X   43587431    G
    rs3810709   X   43587868    T
    rs6610845   X   43588010    T
    rs6323  X   43591036    T
    rs1799835   X   43591085    T
    rs1800465   X   43592016    A
    rs3027400   X   43592763    G
    rs12689575  X   43593479    G
    rs2235186   X   43595428    G
    rs3027403   X   43595678    --
    rs2072743   X   43599521    C
    i5900065    X   43599964    G
    rs7065428   X   43599982    A
    rs979605    X   43601363    G
    rs1803986   X   43603113    G
    rs1137070   X   43603391    C
    rs1800466   X   43603735    A
    rs3027407   X   43604841    --
     
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  5. pogoman

    pogoman Senior Member

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    43516479 rs72382423
    I
    43526943 rs5906883 A or C
    A
    43538209 rs1465108 A or G
    A
    43551260 rs72373490
    I
    43553202 rs909525 C or T
    C
    43557081 rs3027397 A or G
    A
    43559576 rs2283724 A or G
    G
    43565635 rs2179098 A or G
    G
    43571197 rs1800464 A or C
    A
    43574169 rs1800659 A or G
    G
    43587431 rs58524323 A or G
    G
    43591036 rs6323 G or T
    G
    43591085 rs1799835 G or T
    T
    43592722 rs3027399 C or G
    G
    43595428 rs2235186 A or G
    A
    43595743 rs2235185 A or G
    A
    43599521 rs2072743 C or T
    T
    43599964 i5900065 G or T
    G
    43601363 rs979605 A or G
    A
    43602965 rs5905418 A or G
    A
    43603113 rs1803986 G or T
    G
    43603391 rs1137070 C or T
    T
    43603735 rs1800466 A or G
    A
    43604841 rs3027407 A or G
    A
     
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  6. ebethc

    ebethc Senior Member

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    @Gondwanaland - here are my results...

    What's the diff between MAO-a vs. MAO-b?

    Didn't you say quercetin is a MAO inhibitor? is that a good thing or a bad thing?
     

    Attached Files:

  7. Gondwanaland

    Gondwanaland Senior Member

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    Thanks, folks, I have been compiling a spreadsheet, but the fact that some people have double as much os SNPs tested by 23andMe is making this too much work.
    [​IMG]
    From: http://www.cnsspectrums.com/aspx/articledetail.aspx?articleid=1791

    From: http://en.wikipedia.org/wiki/Monoamine_oxidase
    *** here is why vit B2 supplementation is recommended (as per @Sherpa ). I think I didn't tolerate it in the past because I had a downregulation in serotonin production (see below).

    It is a good thing if it makes you feel better, and a bad thing if it makes you feel worse ;)

    In my understanding there are 2 main situations involved here:
    • the serotonin you produce is too much for your enzymes to break down and you get serotonin syndrome symptoms such as anxiety, breathlessness etc
    • this leads to a down regulation in the serotonin production, and you end up with too little serotonin and depression symptoms
    I have been reading with interest Ray Peat's ideas about serotonin being a poison :eek:
     
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  8. ebethc

    ebethc Senior Member

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    thanks. Quercetin really helps me (MAO inhibitor - though not sure if it's MAO a or b or both). Not sure if I have too much or too little, because I have terrible brain fog (too little? hard to say because brain fog can be caused by SO many things) and I do get too anxious.... When I was reading about genetics a lot, I felt that there was some difficulty breaking things down... (ie, neurotransmitters & estrogen, as I recall... but I don't remember which snp/snps)
     
  9. Gondwanaland

    Gondwanaland Senior Member

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    @ebethc I find it difficult to figure out too!
     
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