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Document that explains polymorphisms

Discussion in 'Genetic Testing and SNPs' started by MeSci, Dec 17, 2013.

  1. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    Cornwall, UK
    Hi, all you gene genies!

    I haven't previously been following genetic threads, but have become increasingly intrigued, and remembered that I had had some testing done years ago - I think it was through an item in Action for ME's magazine InterAction (so they're not ALL bad:D) and have managed to dig the results out.

    Although I studied genetics at Bachelors level, I am very rusty on it, and my test results are in a different form of notation from 23andMe and Yasko. The tests were done by the apparently-defunct Sciona/Cellf.

    So I have been trying to work out what mine relate to in terms of some discussions on here - for example mine don't have things like '+/+', '+/-', etc - just the names of two bases, e.g. C,G (and I know what those mean).

    So I've been trying to find translations between mine and what some of you guys have. The conversion resources I've found here don't do what I need.

    While searching the net I found this document which at least seems to lay out clearly and concisely what the various results signify, so maybe some of you would find it useful. Comments welcome!
    Last edited: Dec 17, 2013
    Hanna, Helen and Valentijn like this.
  2. Valentijn

    Valentijn Activity Level: 3

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    Amersfoort, Netherlands
    @MeSci
    23andMe and other genetic testing services also don't use the +/- stuff. That's done by some websites and programs which interpret the raw data to indicate what they think an allele represents risk. Yasko confuses the issue a bit by combining the raw data with the interpretation.
    MeSci likes this.
  3. Helen

    Helen Senior Member

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    @MeSci
    Thanks for the document! I hope the good figure of detoxification and the description of the GST genes will raise the interest for these so important genes -as well as for the others in the detox system.
    Good to hear that you are back on track in genetics with your excellent education. Just take the rust away :)
    Last edited: Dec 17, 2013
  4. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    Cornwall, UK
    You're welcome. There's an awful lot of rust to scrape away though!
    Helen likes this.

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