i've been studying this poll, and it seems well over 50% of the respondents have at least 1 child with me/cfs as well as themselves. There are 3 of us who got me/cfs after our child/children, this causes me the most confusion. i had glandular fever when i was 15yrs, a well known trigger, yet didn't become ill until i was 40yrs old. If XMRV was in me when i was born, passed to me from my mother the way i'm presuming i passed it to my children, wouldn't i of become ill much younger? I don't know for sure of course, but i can only get my head round the XMRV theory if it was given to me sexually, my ex husband had some sort of fatigue syndrome when he was 17/18yrs (well before i knew him), although he has always held down a very challenging job, he did fall asleep at the wheel twice and has always suffered with extreme tiredness. It makes sense that he passed on XMRV to me pre children, i then was carrying it and passed it on before they were born. It then took 2 of the children 8yrs each for it to be triggered via what seemed like ordinary viruses. 1 daughter is healthy(presumably a carrier), and our 5 nearly 6yr old is definately showing more and more me/cfs signs every week, i'm now keeping a log, we are extremely worried! our family situation is so confusing, i just wish someone could unravel all of this & let us know what an earth is going on!!