Hello! There is so much (amazing!) information on this forum, but I really struggle to take it all in. The more that I read, the more confused I get! Brief history: Diagnosed with CFS/ME at 15. I'm now 23. I spend the majority of my day lying in bed, or on the sofa. Though I am able to walk around (to the bathroom, or to get a snack) - I am not able to live independently (cook a meal, do housework, dry my hair, work etc). I can leave the house occasionally for an hour or two, but It takes me a week or so to recover. Back to the POTS. I always feel much better lying down. I've noticed for years that when I stand up my legs and feet will either go very blotchy, or if warm - will go bright red: http://i54.photobucket.com/albums/g110/suze1989/red_zps77e82dc1.jpg I bought a pulse oximeter as I wanted to see what happened to my oxygen sat + pulse when I slept, as I always wake up feeling like death. I haven't done that yet, but I have discovered that my pulse rises dramatically when I stand up. I took some videos. Take a look if you like: Video one shows my pulse jump from 78 to 145 before settling at 112 - that's an increase of 67 beats! http://s54.beta.photobucket.com/user/suze1989/media/1_zps05ef2da6.mp4.html Video two (a bit long - sorry) shows my pulse go from 88 to 136 (increase of 49) before dropping to low 100's and then goes back up to 120 something and then repeats itself a couple of times. http://s54.beta.photobucket.com/user/suze1989/media/2_zps1281028c.mp4.html -- Possibly related history: -When I was 15, one doctor heard a murmur that seems to have disappeared. -I have had a chest Xray (2006) and an ECG (2011) - both of which were normal. (ECG showed tachycardia but I was very nervous) -For a few years I used to get random palpitations (fluttering/thumping/racing) many times lasting 5 hours plus, when I was laying in bed, often starting when I'd roll over or something.. Oddly, it used to go back into normal rhythm when I walked around only to return when I would lay back down. These stopped and I just put it down to anxiety + a severe vitamin D deficiency. I didn't see a doctor at that time as I was suffering from Agoraphobia. I did not feel anxious at home. -My anxiety has improved tremendously. Not really a major issue anymore. But it is, of course, permanently cemented onto my medical records... - Questions: 1) Is POTS a symptom of M.E or is it a separate illness that often occurs in people with M.E? 2) How do I approach my GP about this? He is of the sort that puts every symptom of mine in the M.E/CFS box. Severe joint pain? Normal! Near-fainting episodes? Normal! Ugh, i'm sure you know the type. I live in the UK, so can't just book to see a Cardiologist without a referral. 3)Is my GP likely to take that video seriously? Or it is 'normal' for people like us? Will I come across a hypochondriac? :-( Sorry for the very long post. Congratulations and thanks if you got this far. I'd really value your opinions on what to do next. I'm so confused!