Want some insight from people who do have it so I can figure out which direction to go: 3 years ago I suffered a bad reaction from a drug OD which led to palpitations, anxiety, and fatigue. The palpitations and anxiety have rounded out over the past three years and can be managed. My fatigue however has gradually gotten worse over the last three years and has stabilized to where I am constantly tired. I can exercise, and do very vigorously 4-6 times per week. I lift weights, run, and train for a competitive Rugby team. I do not suffer worse fatigue the next day after exercise, it is the same as when I don't. I do not experience muscle weakness or pain. However I am dead tired almost all day every day. My fatigue is more mental and feels like I didn't sleep well. I also seem to get sick often and have lots of sore throats, ear aches, etc. I have been evaluated by many doctors, endos, neurologists, sleep specialists and usually they either tell me nothing is wrong or they say they don't know. The only "wrong" thing I had was mildly low testosterone levels, so I am on TRT to boost those to high-normal levels, which helps slightly. I tried thyroid supplementation for a TSH slightly over 3 and that just made me worse. The sleep specialist says I have hypersomnia (you are tired and we don't know why) and put me on Ritalin which doesn't seem to be helping. I also have brain fog and my memory is shot. I also have gotten to the point where alcohol hangovers are completely debilitating for me which they never have been before. I have been tested for lyme disease and that came back negative. I also ran a ~6 month course of antibiotics for prostatitis (which is now gone) and felt no better/worse on that, so I can conclude that I definitely do not have lyme disease. At this point either I have a form of PTSD / HPAA dysfunction or CFS. Which do you folks think? Any advice? Thanks a lot.