TLDR?: Labs and summary of case at bottom Hello, I am a college student, with CFS like symptoms all my life: Anxiety, fatigue which is bad but not debilitating, I can still go to school, poor muscle tone, subclinical hypothyroid, tight muscles/ slight kyphosis, intermittent brain fog, space cadet syndrome/ ADDI, anhedonia and lack of motivation, sore for a long time after weightlifting and can't gain muscle, poor self esteem and sensitive . Spatial, executive functioning and fine motor issues, PFC problems and cognitive dysfunction. This all has been tough, especially trying to live up to the guy "masculine" stereotype and pursing (or trying to) my many interests. Anyway, I have had these symptoms as long as i can remember, I did get really bad ear infections and through infections as a kid all the time. Now I have a chronic swollen lymph node on my right side, lowish white count (3.4-4) and occasional ear, burning head pain along with sore throats and the occasional flu like symptoms. I do not have candida, but do have chronic h. pylori and the usual mildish gut issues. Was diagnosed with mild pylouria, zinc deficency, elevated copper/ ceruloplasmin and undermethylation by pfiefer ( based on histamine was 70-90). The B6 gave me neuropathy, even in doses of no more than 200, so I stopped. My serum B6 remained elevated for a long time after that. I tried some SAMe and MB12, both made me possibly feel spacy. Serum B12 and folic acid are normal, B12 remaining really high after mild MB12 supplementation like the B6. Homocystine was around 10.5 and I got a urine organic acid if anyone wants to see. I want to try the methylation protocols but I am afraid due to my bad reaction, and the fact that nothing was super out of reference range on organic acid that I am acutally overmethylating/ eumethylating or that I will methylate mercury into my brain if that is the reason for my brain fog from the SAMe. Magnesium is the only supplement that has helped for sure, my anxiety is WAY better. Zinc possibly helped, but I stopped it because I was afraid it would displace or chelate mercury. Urine metals undecetable, but I have not gotten hair yet. Also I think I might have mortons toe. What should I do? Please Help History and chief complaint(s) 21 y/o male Fatigue, brainfog, cognitive dysfunction, muscle atrophy and poor work capacity, spatial and fine motor dysfunction, intermittant brainfog, high latent inhibition, executive dysfunction, tight muscles. No known onset, symptoms persistant. Scalp infllammation, GI upset, slow motility. Nausea. Histroy of childhood ENT infections. Persistant large right lymph node. Brainfog from SAMe and MB12. Anxiety improved with Magnesium. Zinc helps slightly. B6 200 mg induced parastesia. Summary of Labs H. Pylori Pancreatic Enzyme reduction. Elevated Gluten Antibodies Gut Inflammation White count : 3.4-4 MCV: 89 (80-100) B12 No supp: 800 Zinc: 67 (60-130) Copper: 84 (70-175) Plasma B6 month after stopping : 24 (2.1-21.7) Urine Pyrrole : 14 Histamine: 78 Zinc protoporphyrin: 24 mics/dl ( this is 4 years old) Fasting homocystine: 10.3 OAT: Nothing really in the middle of the ref range, but nothing totally out of whack either. Can Email this. - methylmalonate was pretty low 23andme genetic test for SNPs enroute. Can provide sprectracell test results, but they are 3.5 years old. THANKs!!!!!!!!!