Howdy there folks, so I am currently on round two of methylation therapy after trying a short trial run earlier this summer. The trial run involved Jarrow Methyl B12 Country Life Adeno B12, Solgar metafolin, Jarrow B complex (as per old recommendations of Freddd) L-carnitine, and coenzyme Q. I saw decent results with it, they were not life changing, but it did seem like my sleep was helped, and i slowly gained a little bit of energy. I hit a flatline rather quickly though, and when my supps ran out, I stopped, to see what would happen. I backslid the most on mood and sleep, but it was not that drastic. Decided to try this process again, with updated recommendations from freddd. I have been on round two for about a week now. Here is what i am taking: solgar metafolin (one tablet twice a day) Enzymatic Therapy Methyl b12 (one a day) Anabol Naturals Adeno B12 (one a day) Source naturals L-carn (one a day) Potassium support. I am not taking a multi due to folic acid content and no b complex. No coenzyme either. My results this round are not nearly the same, and my urine color alone, it does not seem like there is much being passed. I seem to be a little bit more neurally alert and my energy seems to be slightly elevated, but round one seemed to be much more impactful. I remember elated mood and a sense of optimism that I do not have this time. I also have an alternate brand of Methyl B12 that keeps crumbling apart when I try to use it, so I switched to the enzymatic. Am I missing something I had the last time? Am I using ineffective brands? Have I simply filled up my B12 stores two months ago? Some help would be appreciated. i really want to make this work, as it helped me before, and i feel it has promise.