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Determining Mercury Sensitivity

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by golden, May 11, 2013.

  1. golden

    golden Senior Member

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    MELISA (Memory Lymphocyte Immunostimulation Assay)

    This blood test was developed by Czech Scientists in Sweden.

    It detects white blood cells that have already reacted to toxic metals.


    Stejskal's pioneering work on CFS shows consistent evidence of Metal Sensitivity in vast majority...

    Fatigue - regardless of the underlying disease is largely hypersensitivity to inorganic mercury and nickel (Neuro Endocrinol Lett 1999: 20: 221.8)


    My Asyra test pointed to high levels of Nickel in my system.

    The contact for the UK though doesnt seem to exist anymore :(

    It was Dr Ian Hyams ...

    In the USA its Douglas MacTaggart

    Does anyone know about this test?
    SickOfSickness likes this.
  2. golden

    golden Senior Member

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  3. Helen

    Helen Senior Member

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    Hi Golden,

    I had the MELISA test done by Vera Stejskal, the researcher, many years ago as I got to know her. It was one year after that my last amalgam filling was removed. The test didn´t show any reaction to mercury though I had been very sick after every removal - and still was. Vera Stejskal said that often there is no reaction in the MELISA test one year after the last filling has been removed.

    But still there probably is a toxic load and due to that negative biochemical reactions that might be quite severe. I have seen several gene tests from people with mercury problems, and both genes in the methylation cycle AND GST-genes in the Phase 2 liver detoxification system have been defect. A low level of reduced glutathione and decreased binding/conjugating capacity makes detox difficult and people have been diagnosed with ME/CFS.

    Helen
    maryb, Wayne, Lotus97 and 1 other person like this.
  4. golden

    golden Senior Member

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    Hi Helen,

    Thanks :)

    Can I just clarify.

    You took the test and it showed negative.

    A year later you had your last mercury filling out.

    So basically, the test did not work?

    Your experience of being very ill after amalgam removal is what i have been researching for my own filling.
  5. Helen

    Helen Senior Member

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    Hi Golden,

    I took the test and it showed negative, and that was one year after I had my last mercury filling out. So the test did work,
    but as the researcher said, this was a rather common result one year after all had been removed. I hope this was more
    clear :). I was ill before the amalgam removal, and got worse during the removal as the dentist didn´t know how to make this as safe as possible. I was exposed to mercury vapor (?) that is very toxic.

    If I get you right you have at least one amalgam filling left? Then I wouldn´t spend money on a MELISA test, only get
    it/them removed by a dentist who knows that you can get sick from them. If he/she doesn´t know, the removal will
    probably not be made safe and to 100%, which is important. www.iaomt.org has some good information if you didn´t know already. After the last filling has been removed; most people start getting much better, but go safe and slowly as recommended.

    If you haven´t had a 23andme test I think this would be of more value for you than the MELISA test. Then you could get to know your genes in the methylation cycle, and your DetoxiGenomics: most important the GST-genes.
    Wayne and golden like this.
  6. golden

    golden Senior Member

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    Oh I see. Thank you :)

    Wouldnt it be a good thing to have verified on your medical records - metal toxicity?

    I only have one filling. However problems occurred from several things around this time including a vaccination and a virus. So Before I 'risk' removing it , I want to know if it is actually a problem for me....if its not I would prefer to just leave it there...

    I just havent got to grips with the 23me test yet nor the methylation... so I am bypassing it ha ha and trying

    a hap hazard spontaneous protocol :)

    Good to hear from you direct over this issue....

    Would you say removing the fillings made you better now?
  7. golden

    golden Senior Member

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    p.s. I am awaiting an email response from melisa as to the cost!!

    Its a bit disconcerting that the prices arent on the website! (not that i can find anyway)

    hope its affordable :)
  8. Lotus97

    Lotus97 Senior Member

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    If you got very sick after each removal are you still glad you got your amalgams removed? I can't afford to get mine removed, but I'm not sure I want to even if I could afford it because it seems risky.
  9. Helen

    Helen Senior Member

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    Yes, of course it could be a good thing to have a MELISA test. But it doesn´t show toxicity if positive. It shows allergy to different metals -or not. When I took the test it was a panel of many metals, not only mercury. I have studied mercury-related health problems for 20 years and followed many, many sufferers and their signs and symptoms and nickel allergy has been very common among people with mercury problems.

    I would never leave just one filling as every time you chew with it, get hot food or drinks on it or eat sour things this will emit mercury. A study, unpublished of political reasons, showed that mercury also emits from amalgam fillings in front of some PC´s (computers ?). I worked with one of the worst PC´s when I got sick at the department where this research was made.

    Yes, the removing of my fillings made me very much better. I was almost bedridden when I decided to have them removed. I have met many people who, after their last removal of amalgam got their health back. They probably have better genes for detox then we have that end up with ME/CFS.

    Today I am convinced that the genetics that is involved in detoxification, and of course the exposure, "decides" how sick you are. If you have the real bad genes you are prone to get sick even from removal, if not carefully made. And it is also important to support the body with the right vitamins, minerals and other substances.

    Difficult topic for me to discuss in English, but I hope it is possible to understand. If not, just ask!
  10. Helen

    Helen Senior Member

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    Yes, the removal saved my life I am sure, and if it had been made properly I had surely felt even better today. I am really sorry that you can´t afford a removal. I know that you, like me, appreciates Rich´s work, and if you listen to his seminar in Sweden he talks about mercury and methylation. Mercury is supposed to be the strongest stressor to methylation. It disturbes the metabolism of B12 among many other processes. People that have been taking B12 during the time for removal seem to get much better than others.


    Helen
    Lotus97 likes this.
  11. maryb

    maryb iherb code TAK122

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    I too got much worse after amalgam filling removal - and that was with a specialist dentist!!
    Took me 6months to get back on my feet, and never really returned to pervious levels - I have another 3 fillings to go - I'm having them removed in the next few months - hopefully with some specialist support with chelation and by a different dentist... Cheyney recommends removal of one a year , but I'm running out of time.
  12. ukxmrv

    ukxmrv Senior Member

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    Dr Hyams was my doctor in London for a while. I had a lot of tests through him but can't remember if we did this one. The Mercury tests that we did do were negative for me.

    Dr Hyams was brought before the GMC and then left the UK for Canada.
  13. Lotus97

    Lotus97 Senior Member

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    I'm glad to hear that getting them removed helped you. I'm not sure if amalgams made my health worse or not because I had Lyme for a long time before I got them. It's true there were periods after getting my amalgams where my health did get worse, but it happened at least 6-12 months and afterwards both times occurred after periods of oxidative stress. I also think my Lyme got reactivated because my rash appeared before each time my health got worse. I don't want to rule out mercury as a contributing factor though. Would getting tested for mercury give me an indication of whether or not I need to get my amalgams removed? If so, which test would be the best (and cheapest)?
  14. Lotus97

    Lotus97 Senior Member

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    I have read what Rich has said about mercury and methylation, but there doesn't seem to be a one-size-fits-all approach in regards to methylation, chelation, and amalgam removal based on his posts in the past year or two:
  15. Helen

    Helen Senior Member

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    I am sorry to hear that you got worse after the amalgam filling removal. Specialist dentists often claim that amalgam and mercury in the teeth is not toxic- how that can be?? But if the dentist believe it is toxic and might compromise your health, then they use to be ok if they follow the protocol for as safe removal as possible.
  16. Helen

    Helen Senior Member

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    The experience we have in the IAOMT in Sweden is that there isn´t any valid test to see if a person is intoxicated from mercury. MELISA test can show an allergy.
  17. Helen

    Helen Senior Member

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    Sorry to hear that you have Lyme as it also is difficult to treat for many. Symptoms from mercury can occur whenever after you have got them as so many things can increase the "output" of mercury in your body. As far as I know there is no test that gives a valid result if you are intoxicated. I think the 23andme test would give a clue of risks of blocked methylation and/or impaired detoxification in the liver phase I and II (detoxigenomics). The result might give you an idea of the risks with an amalgam filling removal. But it is also about the dentists knowledge and your antioxidant levels.
    Lotus97 likes this.
  18. Lotus97

    Lotus97 Senior Member

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    So the test Cutler recommends isn't accurate? I don't know much about his protocol, but some people swear by it. And I think Rich said something about a DMSA provocation test. I realize you just said that there is no valid test so I hesitate even asking you these questions...
  19. Helen

    Helen Senior Member

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    I wish I had good answers to your question...Could you please send me a link to the test that Cutler recommend? As long as some people get more sick of a specific protocol it isn´t safe, and that is the most interesting question to get answered before starting up with one. There are always success stories but with our individual differences I think only gene testing can give an idea of the risks and how to go on.

    As provocation tests release mercury from places where it has been stored, and if you can´t bind it, due to lack of glutathione and/or bad binding/conjugating capacity or of other reasons, you might get very bad from it (or any detox protocol).
  20. Helen

    Helen Senior Member

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    I will read the inputs from Rich and will be back later

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