Alright so i just typed out my entire post and accidentally deleted it. yay So I was having very positive reactions to Metafolin 1000mcg. Was going up to like 15 mg well tolerated. mb12/adb12 in check, playing with levels. LCF/Potassium in check as well. Got myself some generic Deplin (L-Methylfolate Calcium) thinking this is going to be the same experience, only now I could really ramp it up to the levels that I apparently need. This has not been the case. It is a noticable difference, it is not nearly as immediate and powerful, it kind of comes and goes, it is unreliable and it just doesn't feel the same as Metafolin though I was under the impression it was bioidentical. Who knows if the additives in it are making the difference or not but this is not the same experience for me. I've made it up to 45 mg / day before I conceded to the fact that this just isn't the same stuff. Has anyone else had a similar reaction? Metafolin was exactly how I wanted to feel, it was very good for me. Now I'm looking for alternative sources of methylfolate and I'm thinking about Magnafolate-C, it's supposed to be identical as well, and without all the ridiculous additives of pharmaceuticals. Does anyone have experience with Deplin, L-Methylfolate calcium, or Magnafolate-C? I'd like to make a purchase of the Magnafolate to see if I react similarly to how I did with Metafolin but if I could gather some information on others experience before shelling out another ridiculous amount of money that'd be great. Thanks!