First question: My son and I have several deletions-GSTT, among others. Is a deletion worse than a homo SNP, or is it a case by case deal? Too much conflicting info and my brain can't process it effectively at the moment! 2nd:23andme shows me as homozygous GG for L432V, related to estrogen clearance as I understand it. Stirlings app lists the troublesome allele as C, which would indicate no issue. However, my estrogen 2:16OH ratio has been perpetually skewed despite Ca Gluconate (glucarate?) and high doses of DIM, which would, on the surface, indicate that GG is,indeed the troublesome allele, unless there's another factor at play, of which I am currently unaware. Any thoughts on the subject? (either one?) I'm puzzled. Thank you!