Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Defensins associated with slower HIV progression

Discussion in 'Other Health News and Research' started by raul, Feb 25, 2010.

  1. raul

    raul

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    http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009436

    [From the abstract]

    Conclusions/Significance

    High production of α-defensins1-3 by immature DCs appears as a host protective factor against progression of HIV-1infection, suggesting potential diagnostic, therapeutic and preventive implications. This protective effect may arise from the activity of α-defensins1-3 to damage the virions prior and/or after their internalization by immature DC, and hence favoring a more efficient viral processing and presentation to HIV-specific CD4+ T cells, without or with a minor rate of transmission of infectious HIV-1 virions
     

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