Hi, I have only just started reading Olso's web, thanks to Alex. It might be hard to believe because i have been around these cfs forums for a few years now and know about Olso's web but never got to it, read snippets here and there off the internet but ?? Anyway the first 2 chapters really struck a cord, the rest of the book probably will too but, his original cfs patients he tested for ebv had very high EBV titres but negative to EBNA which is suppose to keep EBV latent and was found undetected in Pattersons patients. In australia i cant get titres measured but originally had a positive to ebv but a test last year showed negative to EBNA which is usuppose to be life long titres. It also mentions white blood cells are down which my neutrophils are often down. He does state that at the time they were calling it chronic ebv but thought it was due to the immune system and a guru he consulted with who was the best at the time for testing these different ebv titres said that he only sees it in children with aids and a small number of patients with rare immune defiencies????? Is this XMRV. I also struggle with the idea that alot of docs at the time didnt have alot of patients in the past come to them for fatigue, i think fatigue makes up alot of the clientel of the average doctor these days and i think cfs is very prevelent these days and people dont know they have it unless they get it alot more severe. Are there others who have had mono from ebv but negative to EBNA???? ALot of people say that there docs tell them they are negative to ebv but i wonder if they are getting the riht tests done, also people tended to see these results after a few months of being sick so maybe takes a short while for this to occur. I think the ebv reactivation is just showing some underlying immune problem, mm. cheers!!!