Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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D-Lactate & Panic Disorder

Discussion in 'The Gut: De Meirleir & Maes; H2S; Leaky Gut' started by MEKoan, Sep 16, 2009.

  1. MEKoan

    MEKoan Senior Member

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    D-Lactate & Panic Disorder - ME/CFS Anxiety

    1990:*Gorman J M; Goetz R R; Dillon D; Liebowitz M R; Fyer A J; Davies S; Klein D F
    Sodium D-lactate infusion of panic disorder patients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology*1990;3(3):181-9.

    Nineteen patients with panic disorder received sodium D,L-lactate (racemic) and pure sodium D-lactate infusions in a pilot study. Sodium D-lactate, which is less metabolically active than L-lactate, produced panic attacks in half the patients. D-Lactate also produced hypocapnia and alkalosis, indicating hyperventilation. These findings suggest that metabolism of lactate is not necessary for the induction of panic in susceptible patients. D-Lactate appears similar to other agents that cause panic in its capacity to stimulate respiration in the preliminary study.
     

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