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Cytochrome P450 Testing In High-dose Opioid Patients

Discussion in 'Other Health News and Research' started by Kyla, Jul 27, 2016.

  1. Kyla

    Kyla ᴀɴɴɪᴇ ɢꜱᴀᴍᴩᴇʟ

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    Canada
    http://www.practicalpainmanagement....chrome-p450-testing-high-dose-opioid-patients

    Excerpt:
     
    Skippa and actup like this.
  2. Skippa

    Skippa Senior Member

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    Ooh hello, anyone know what else I can look out for that is symptomatic of CYP450 deficiencies without actually getting tested?
     
  3. cfs6691

    cfs6691

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    Shouldn't CFSsufferers who are intolerant to chemicals or have had an adverse reaction to medication eg antibiotics,anabolic or contraceptive steroids(such as myself)also be tested since the cytochrome p-450 enzymes break down medications and other chemicals that need to be eliminated from the body?I have had adverse reactions to antibiotics and to contraceptive steroids,I suspect that I and other CFSsufferers may have undiagnosed liver damage that affects the body's ability to eliminate xenobiotics.I am not insured and I cannot afford to have genetic testing done.I am also wondering if it would serve any purpose even if it turned out that I have a mutation or polymorphisms since researchers are focused on their ideas and theories.I would probably be able to announce it by starting a thread but unless there is some way of having testing done that is affordable to someone who does'nt have many resources I don't see the point unless soneone keeps track of those findings and follows up(eg liver biopsy since blood tests are not reliable in order to rule out liver disease/damage or other tests if genetic testing points out to another organ/system being affected).
     

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