My first forum post. Great Community. Forgive me for starting a new thread I have MS and have been on an quest to solve what i believe may be a contributing factor to many problems I associate with my MS and Crohns. I've been scouring the WWW and working with my doc (who also has MS) and my long-time Gastroenterologist but no breakthroughs . . . until I stumble on Phoenix. Holy B12, Batman! I had a resection of my terminal ileum in '91 as a result of Crohns and that is where my affair with B12 begins. I started taking b12 injections every 5-6 weeks (cynocob) and since MS diagnosis gradually more often until the present when currently I take every 72 hours. This prevents a crash (fatigue) and a slight but noticeable improvement in a few 'MS' symptoms. My serum B12 levels are off the charts (1400) and my Gastro thinks I'm crazy but I explain the twice weekly boost I get 24 hours after taking it. I've tried taking 15mg methylcobalamin sublinguals tabs with no results until today when I kept under my tongue longer than usual (after reading some posts here at PR). Fatigue noticeably improved, numbness in hands less and slight improvement in mobility. I'd like to know which B12 protocol/regimen folks around here think that I should try? Surely I have malabsorption issues of some kind? Perhaps there is a regimen forum around here where I could post my complete regimen that I could then point to in my signature? I once read that there is not ONE MS symptom that cannot also be explained by a B12 deficiency! While I'm pretty certain that I have MS, I would like to know if my current love/hate relationship with B12 could be implicated in my current MS struggles. Lastly, I've had my Internal Jugular Veins ballooned twice in the last two years with amazing results each time . . . but they only lasted 1-week each time. Re-stenosis is a common homeostatic response in the jugs apparently and they don't always take nicely to stents. I've heard of one girl with CFS that had her veins ballooned with some amazing results. The most common symptom improvement cited by MS patients treated for CCSVI is In the fatigue department. My fatigue resolved 100% after my first procedure. Allowing oxygenated blood to get to the brain does wonders! And Neurologists explored a vascular connection to MS for SEVENTY 70 years. Now they are trying to discredit the idea. A lot of tails between a lot of legs? When I mention CCSVI and the 70 year MS-vascular timeline to my Neurologists, they look like like someone flew a plane into their building! Ouch! Apparently Paulo Zamboni and a neurologist, Zavidinov spoke before Canadian Parliament today.