Any one found duloxetine helpful for lower back pain? Facet joint ablations i have for facet joint arthritis do help but dont take all the pain away but tramadol is very helpful. Of late the effects of the abalation i think are starting to wear off, not quite getting 12 months worth of pain relief out of it. So looking for alternatives to keep me going before i need another ablation. Currently i take 200mg tramadol SR and understand interactions between tramadol and duloxetine(serotonin syndrome), thinking of talking to my doc about duloxetine and add 50mg tramadol when needed, this is dependant on if any reaction occur at that dose. ANti-inflammatories are out if used more then occassionally as i have had previous GI bleeds from chronic use of NSAIDS.