I know some slow release tabs are effected by being cut and some arent as they are made to disolve slowly. Anyway i use a 200mg SR tablet for back pain but sometimes its not enought to get me through the day and need a top up, so i was thinking instead of getting a presciption for a lower dosage pill as well it would be easier to cut the stronger pills into 1/4, not that 50mg slow release or immediate release would make a difference, but does anyone know if it is effected?? Hopefully a short term thing for a couple of months until i can get a procedure done for my back which has beeen successful in the past but its not effective for longer then 12 months. cheers!!!