My background: I had mono in August 2011. I had 4 months of hell afterwards, and I have NEVER FULLY recovered. Currently 2 years of fatigue and loss of appetite and exercise intolerance - I feel at a scale 5/10 http://www.treatmentcenterforcfs.com/energy_index_score/index.html After trying everything on the planet from thyroid medicine to supplements, the only things left are anti virals . I am currently on Valtrex 1.5 grams 4x daily - started 2 weeks ago. -So far the experience is 50/50. I had a couple of good days, but after exercise I crashed bad. -I am also feeling worse than before. I know its too soon to judge because a "herx" is possible, but i heard good results from FAMVIR without side effects. I read the posts and member HEAPSREAL tells people FAMVIR worked wonders for him. Currently i'm covered by insurance. Although I do not have a doctor that is very knowledgeable on the topic, he is willing to try these antivirals based on Dr. Martin Lerner's protocol from Michigan. If I get FAMVIR he will prescribe it to me at the same dosage at 1.5g 4x daily Im wondering if the recovery time is faster on FAMVIR than on VALTREX? Also, what about VALCYTE? I know liver monitoring is needed (NAC might help), but is it equally effective? I'm looking for someone with experience on these anti-virals who has made good progress. My goal is to reduce my fatigue so I can get my life back instead of sleeping 12 hours a day and waking up tired. I'm wondering if I will ever recover to 100%?