Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Cucurmin and Herxheimer?

Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by LisaGoddard, Feb 23, 2013.

  1. LisaGoddard

    LisaGoddard Senior Member

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    Hi,
    After a few days of taking curcumin, I get a really horrible flu like feeling. This has put me off it. However, I wonder if it is a herxheimer reaction and if anyone has a similar experience? I gather curcumin is anti-inflammatory so I'm not sure why I should be getting a herx. Any advice?
    Thanks,
    Lisa
     
  2. PGHCFS

    PGHCFS

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    I have also read that curcumin increases th2 and cfs patients, some believe, are already th2 dominant. This may explain a worsening of symptoms (or not, really I am clueless). I gave up green tea and curcumin while I try to level out my th1/th2.
     
  3. maryb

    maryb iherb code TAK122

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    Lisa I can't tolerate curcumin either, makes me feel quite ill - no idea why.
     
  4. LisaGoddard

    LisaGoddard Senior Member

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    Thanks guys. Good to know I am not the only one. I found something a little while ago that said in rats, it increases th2 when given in low doses and decreases th2 at high doses. I won't try it again - not worth the risk.
    Thanks again.
    Lisa
     
  5. Lotus97

    Lotus97 Senior Member

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    I've been experiencing herx from probiotics recently. I considered it was from die-off, but I read recently that probiotics can sometimes initiate a Th2 response in people so I'm considering that a possibility too. That said, a quick Google search shows that curcumin possesses antibacterial, antifungal, antimicrobial, and antiviral properties so you might just being experiencing die off. Also, I'm not sure if these lists about Th1/Th2 stimulants mean that they all active the same way. While curcumin is listed as a Th2 stimulant it also is supposed to inhibit cytokines.
     
  6. CedarHome

    CedarHome

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    So, I know this is an old thread but it's so handy when all the info on a particular item stays together..

    RE: Finally figured out how to take Cucurmin?!


    I've seen all kinds of recommendations for cucurmin- take with food, on empty stomach, with snack, before bed, anytime of day.

    I have been trying a cucurmin/ bioprene tablet from Mega Foods ("Turmeric STRENGTH").
    Adding it in with other supplements at a meal= no effect.
    Taking it with snack before bed= wired all night.

    Taking it with fat (peanut butter in this case) an hour before a meal= WHAMMO major effect.

    About 4 hours after taking it I went into an intense -but- just- bearable episode that included:
    -Slight difficultly breathing, almost like a very mild anaphylactic response (at first, this went away)
    -Transient (bearable) joint pain (it was actually almost interesting to feel the pain move throughout my body from place to place)
    -Sinus pressure
    -"Helmet" type headache
    -Inability to anything but lie down, doze and ride it out

    The intense part lasted about 8 hours (luckily mostly evening) and then I was able to sleep fine

    The only point of comparison I have is the first couple times I took NAC. Since I do seem to have a chlamydia pneumonia (CPN) load, and NAC is supposed to go after CPN, I assumed that the reaction was NAC hunting down and chomping on the CPN. After a while (few days? week?) I had no obvious response to NAC anymore.

    So I'm wondering if the cucurmin was doing the same thing somehow, allowing my body to go after pockets of infection it can't usually get to.

    Remembering "go slow" I might take a couple days to recover equilibrium before trying again. It felt therapeutic but crazy. Will do lots of detox support today.
     
    sb4 likes this.
  7. ljimbo423

    ljimbo423 Senior Member

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    Hello @CedarHome - Both curcumin and NAC can raise glutathione levels. Glutathione is a powerful detoxifying agent and can cause mild to severe detox symptoms.

    Both curcumin and NAC cause me significant detox symptoms that are dose related, the higher the dose, the worse the detox symptoms.

    Jim
     
    CedarHome likes this.
  8. CedarHome

    CedarHome

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    aha. Thank you!
     
    ljimbo423 likes this.

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