I have read the first and the last page and really think the arguement about me and cfs should be left alone until there are better biomarkers which hopefully arent too far away. I know finding a biomarker is hard when there is a mixed bag of patients but i think the vast majority of patients with either diagnosis have the same condition just in varying severity and symptoms. The nk bright cell dysfunction to my knowledge is mainly found in cfs/me, rheumatoid arthritis and MS patients??? i think?? Last i heard PHANU are looking into how to seperate these 3 conditions through further nk function testing. If they find a specific nk dysfunction only common to cfs/me, then i hope they get rid of both names as both names have been muddied beyond repair that many doctors will never recognise as then they would be admitting they were wrong. NK neuro-immune dysfunction for example or something very descriptive of the illness. I think ME is a fine description but the term is now damaged and past its used by date. cheers!!