Hi all, A couple of questions that have been bugging me for a long time: 1) Does anyone have any research articles that back up the claim by Dr Yasko and others that a homozygous CBS C699T mutation up regulates enzyme activity by 10x or anything close to that. Stuff I have seen so far which looked at homocystiene levels of people with and without the mutation showed fairly nominal variations (i.e. like 10-15% or so reductions in those with the mutation). Nothing close to the heavy up-regulations claimed by Dr Yasko et al. 2) Has anyone seen a source other than Dr Yasko or Heartfixer that confirms that sulfates increase the fight or flight response? And if so, what is the explanation given? Thanks ahead of time.