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Could vitamin D3 overdosing may be contributing to autoimmune diseases including CFS?

Discussion in 'General Treatment' started by Fejal, Oct 23, 2010.

  1. Fejal

    Fejal *****

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    Here's the basic theory quoted from my comments in another thread.

    I just found more evidence for a link between autoimmune disease and cell receptor changes due to uv light like what we see in D3 ingestion:

    If you think about the way people have managed D3 in the past thousand years, there was no D3 available orally so what would happen is that people would get sun exposure for 3/4 of the year then in the winter be deprived-allowing the levels to go down. Now because there is supplementation in the food supply people lack that wean down period and overdose. Additionally, the daily dosing desensitizes the receptors to lower their activity.

    I think the solution is to use vitamin D2 dosed weekly rather than D3 daily. This allows the body to use its feedback control mechanisms to control the D3 levels.
  2. garcia

    garcia Aristocrat Extraordinaire

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    Oh please!

    More Marshall-propaganda spam.
  3. Fejal

    Fejal *****

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    Are you crazy? This has nothing to do with them.
  4. garcia

    garcia Aristocrat Extraordinaire

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    Your argument is full of basic errors. For example D3 is not the active form 1,25 D as you state.
  5. Fejal

    Fejal *****

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    I doubt your assertion that these errors exist and easily found a source that shows your statement that D3 isn't the active form of vitamin D to be false.


    You are also wrong because the Marshall Protocol explicity bans all vitamin D and doesn't discriminate between ergocalciferol (25D) and cholecalciferol (1,25D) because it erronously believes 25D inhibits the VDR in any amount and dosing schedule.

    Please refrain from posting more false information in the future.
  6. garcia

    garcia Aristocrat Extraordinaire

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    Ok I grant that you are saying something different from the Marshalites (as you say they say to avoid all Vitamin D, where as you are saying avoid D3 only).

    But I repeat Vitamin D3 is *not* the same thing as 1,25-D.

    Look here:
    1,25D is also called calcitriol:

    http://en.wikipedia.org/wiki/1,25-Dihydroxycholecalciferol

    Vitamin D3 is called Cholecalciferol

    http://en.wikipedia.org/wiki/Vitamin_D3
  7. Fejal

    Fejal *****

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    It's the same thing. Don't jump to conclusions.

  8. jace

    jace Off the fence

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    This exchange shows clearly why I prefer another forum. Constructive debate is far more illuminating.
  9. garcia

    garcia Aristocrat Extraordinaire

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    It is not the same thing. "Active form" in this context means chemically it is a different compound, i.e. it has to be converted.

    In the same way that T3 is the active form of T4. That doesn't mean that T3 & T4 are the same thing.
  10. Fejal

    Fejal *****

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    Are you saying that wikipedia is wrong? I don't see your point. I think they are just pseudonyms and you are misreading too much into it.
  11. garcia

    garcia Aristocrat Extraordinaire

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    No, wikipedia is right. The links I posted above were to 2 different wiki articles showing that D3 and 1,25-D are different substances.

    They are not pseudonyms. Understanding the difference between the two would help you perhaps refine your theories and see any errors in your argument.
  12. lansbergen

    lansbergen Senior Member

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  13. garcia

    garcia Aristocrat Extraordinaire

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  14. Fejal

    Fejal *****

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    Thanks for the explanations. Actually the supplement I was using, cod liver oil, is D3 (I just learned) so this is moot.

    But interestingly, three hours after taking 2000 IU of D3 my body temperature dropped to 95.2 F (was previously 97.8 F) so obviously this is an overdose. This supports what I was saying about there being fewer receptors. I'll be watching to see how long the effect lasts. I didn't have this response yesterday when I dosed 400 IU 2x.

    Timing the temperature depression now. So far is on the way quickly back up to 97.2 after 40 minutes with supplement dosing.

    I found a citation showing that a period of body temperature depression is common with Jared-Herxheimer reactions.
  15. dannybex

    dannybex Senior Member

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    Now that's both ironic and funny.
  16. Fejal

    Fejal *****

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    The only stupid questions are the ones that you don't ask heckler.

    I checked with a pharmacist before posting the thread and she was misinformed as well.
  17. Martlet

    Martlet Senior Member

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    Moderator: I have been following the posts in this thread and while argument has been strong, have not felt a need to intervene until now. Calling someone a heckler is out of line. Now, I am asking everyone to calm down and get back to the topic at hand without further name-calling, or I will close the discussion.
  18. Fejal

    Fejal *****

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    Martlet do you not see the offensive nature of Bex's comment that I intentionally misinformed the board? That is heckling so there is nothing wrong with calling him out on it.

    So far there has been no comment on the main idea of the thread, that sustained overdoses of vitamin D could cause receptor insensitivity and reduced immune response. I think this is a factor in my own bartinella spp infection.
  19. rlc

    rlc Senior Member

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    hi fejal i noticed your strange reaction to vit d and thought this may help, i don't know if you are taking any other medications or have been investigated for other contitions that may cause this but here's alink about it http://www.rxmed.com/b.main/b2.phar...s/CPS- (General Monographs- V)/VITAMIN D.html If anyone is taking or considering taking codliver oil they need to know this if they don't already link http://www.essortment.com/lifestyle/possiblesideef_slyf.htm as for the argument about the marshall protcol i think i'll stay out of it, but i would advise anyone considering it to read this link about the complications of vit d deficiency first http://www.buzzle.com/articles/vitamin-d-deficiency-symptoms.html have fun all the best
  20. Fejal

    Fejal *****

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    I had my MD check out my hyperparathyroid hormone level re: the hypercalcemia but he didn't report anything abnormal which is pretty incredible given I was hypo at 17 for 9 months. I just started supplementing to get it back up so there's no way I can be hyper vit D. Moreover, cod liver oil is D3 not D2 (ergocalciferol).

    If someone is infected with an L-form bacteria I do think it is preferable to not take any D because otherwise the active D is so high it demineralizes the bones. I had a lot of tooth erosion before I went hypo D, so going hypo probably saved my teeth.

    The solution is to id the bug, supplement to correct blocked apoptotic pathways and then take D.

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