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Could Copaxone Help Us?

Discussion in 'Latest ME/CFS Research' started by Daffodil, Aug 3, 2014.

  1. Daffodil

    Daffodil Senior Member

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    Hi, all. I was reading about the plasmacytoid dendritic cells and how they can disregulate the immune system after a triggering event such as viral infection (as you know, these cells were implicated in CFS in the DeMeirleir/Lombardi paper).

    In this paper, it mentions that glatiramer acetate (copaxone) can help regulate plasmacytoid dendritic cells so I am wondering if this might help us.

    http://brain.oxfordjournals.org/content/129/5/1293.full.pdf

    I also found a forum where a woman says her diagnosis was MS, she took Copaxone and improved. Later on, her diagnosis was changed to CFS.

    http://www.healingwell.com/community/default.aspx?f=15&m=2080092

    Copaxone patent just expired....
     
    Last edited: Aug 3, 2014
    alex3619 and MikeJackmin like this.
  2. Ema

    Ema Senior Member

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    Midwest USA
    Copaxone seems to be a Th2 shifter. Many think that we are already stuck in Th2 mode so I'm not sure if this would help or not.

    It doesn't seem to have a ton of terrible side effects though so if the cost were reasonable, it might be worth a try.

    I'm certainly interested to hear about others experiences with it too.
     
  3. Daffodil

    Daffodil Senior Member

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    You are right.

    Anyway, some toll like receptor modulator could help us eventually...judging by copaxone's success, this approach could work very well in our autoimmune disease:

    http://pharmrev.aspetjournals.org/content/61/2/177.long
     

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