Has anyone taken these during the course of ME, and if so, what was the effect? Did you have any unusual effects, and did it have any effect on the ME in general? I'm not suggesting anyone try this - only curious if anyone has. Oral corticosteroids can be dangerous, especially with long term use, but whether or not they affect the disease process or symptoms at all could give information about how it works. So if any of you have, I'd very much appreciate a report of how you felt it helped or worsened your ME (or did nothing) as well as the duration of the effects.