I've been treating my CFS at the moment on all possible levels (restoring mitochondria performance, restitution of neuronal balance & neurohormones, immunmodulation, dieting). I've noticed that my energy increased, brain-fogged lifted, and so was thinking that all those measurements would be working. The last two days though I felt ill again, and really, really tired... the only thing I've changed was, that I haven't taken my 'Nytol' sleeping pill, which active ingredient is an antihistamine. I almost couldn't sleep, woke up several times stressed, have a running nose, swollen eyes and just feel ill... even after taking my mitochondria-neurohormones-immunmodulation cocktail which has normally in the morning an immediate pick me up effect. I started to think about when my CFS started, and remembered it was around 1 year after I got severe hayfever for the first time. (At this time, I also developed a nickel allergy and once my face got so swollen and red due to a chemical allergy, that my parents had to take me out of school for two weeks.) The hayfever got much milder since, the episode of the reaction to the chemicals was nearly forgotten, and with all the other symptoms coming up from CFS, I haven't paied too much attention to all that... It made me thinking now, that maybe the trigger for (my) CFS were errant allergical reactions of my immunesystem which then had an effect on other body functions? So, I am wondering, how many of you CFS sufferers out there have/had hayfever or other allergies, and has the first time occurred somehow in a related timeframe when your CFS broke out?