Has anyone developed any sort of connective tissue problems? After taking methylfolate, methylcobalamin and p5p I have developed EDS type symptoms, as well as receding gums and loose teeth (collagen related). Also feel my chest bone click a lot. These clickings/cracking very weaker with time and looser/more unstable....I feel I won't live even a semi decent life if I'll need reconstructive surgeries, spend all my time in a wheelchair, and need braces for my major joints. Has anyone gotten any help with their connective tissue issues?