Still learning a lot about the disease so I'm grateful for all knowledge 1. I read that the immune system seems to be running high the first years, and then get weakened. What does this mean when it comes to remission (if you are one of the lucky ones I mean)? Any signs that points to this theory of high/low happening? 2. I also read that ME patients usually don't catch colds and so on because of the immune system working so hard. And that colds are actually a good sign. But at the same time many patients report having frequently infections, viruses and allergies. Some people are always catching colds and so on. If the immune system is on high mode, shouldn't we be more protected from infections and so on?