Hi there, Can anyone explain why a normal blood test for B12 is not really telling us what is going on? My naturopath says it's like measuring what's in the cupboard but that's no good if you can't open the cupboard door... But I'd like a more technical answer so I can figure out what to do. I am MTHFR C677T+/+ and so have folate and B12 need. Other genes have been tested too and I know what each one may express. My blood test was "normal" last October, now after taking daily: 2mg of adenosylcobalmin and some liposomal B12, for some months my doctor has hit the roof - I had a blood test because I had chest pains - my B12 is 1034 pmol/L (Range is 180 - 740). Naturally she wants me to stop taking B12 but my naturopath says I need it. I can't take any folate as folic acid doesn't convert and Methyl donors overload me and I feel like I have flu. Hence no methyl B12 either. My folate blood test was 2594 (Range: greater than 630). My memory is better but I haven't noticed any change in other symptoms on B12. I'm also on Mg, ATP Fuel, C, Silymarin, and various amino acids with B6 and Zn mixed in, as I measured zero for all aminos on a Urinary amino acid test. My active B12 was ok. What to do? Thanks.