Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
Discuss the article on the Forums.

COMT, VDR and Dopamine?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by EvanB., Aug 26, 2013.

  1. EvanB.

    EvanB.

    Messages:
    21
    Likes:
    14
    I am:
    COMT V158M AA (++)
    COMT H62H TT (++)
    VDR Taq AA

    I have had issues with low dopamine... do these snps seem to be consistent with that?
     
  2. Valentijn

    Valentijn The Diabolic Logic

    Messages:
    14,104
    Likes:
    44,044
    VDR Taq AA is the faster version for producing dopamine (though it's a pretty small increase), and COMT +/+ are the slower versions for breaking down dopamine. So these SNPs don't account for your low dopamine problems.

    But there are other VDR and COMT mutations which might also be relevant. I've compiled lists at:
    http://forums.phoenixrising.me/index.php?threads/interesting-vdr-variations.24480/
    http://forums.phoenixrising.me/index.php?threads/interesting-comt-variations.24672/
    Using those lists current requires manually searching through your raw 23andMe results after downloading them.
     
  3. EvanB.

    EvanB.

    Messages:
    21
    Likes:
    14
    Thanks so much for all the responses Valentijn!
     

See more popular forum discussions.

Share This Page