COMT MB12 rage

[picante]

Both he and I get sleepy from it

Maybe at that point (the rage episode) it would have made him calmer and more relaxed. Even sleepy might have been better than full of frustration & anger (just thinking of my own preferences, LOL).

 

[Gondwanaland]

Are things better for your husband today? Hope so.

Thanks for asking, he is depressed, sleepy and his lower back is locked up by pain

symptoms of dopamine excess, other than anxiety.

Anxiety from dopamine? I though too much serotonin would cause that

until ... the feedback mechanism kicks in, and they start making less of it!

Three large doses and he was drastically better by bedtime.

There is something re B3 that I forget now, cholesterol? high blood sugar? I don't know... DH triglycerids and insulin are really high
For me high dose folate depleted my B1

B2 or B3 in the B complex were depleting my thiamine

For me high dose folate depleted my B1

I got the return of an old rash from supplementing benfothiamine
I wonder if it would be a good thing to give DH benfo for his insulin issues

Thank you so much ladies for helping me think!!!

 

[Gondwanaland]

How about giving my DH lithium? His serum B12 is high (>700)...

 

[picante]

Lithium is something I am not at all familiar with.

 

[picante]

My husband is taking B2 to try to quit the SSRI, but had back pain, and I used 1,200 mcg of B12 drops to massage his back.

B2 made my low-back pain (inflammation) come back. Freddd said the B2 depletes mefolate, and one symptom of deficiency is inflammation.

 

[picante]

Actually the info from that video is very confusing as the dr recommends methyl suppd to treat +/+COMT
http://beyondmthfr.com/2014/05/07/how-to-balance-comt-and-mao-in-the-brain/

Very confusing, as many +/+ COMT people here cannot tolerate any more than tiny doses of MeB12.

 

[Gondwanaland]

B2 made my low-back pain (inflammation) come back. Freddd said the B2 depletes mefolate, and one symptom of deficiency is inflammation.

Very confusing, as many +/+ COMT people here cannot tolerate any more than tiny doses of MeB12.

If you watched the video it explains that the inflammation comes from slow breakdown of catecholamines. B2 increases neurotransmitters and I assume MB12 and Mfolate will be used up in the breakdown, especially if someone has the slow version of the enzymes.

 

[picante]

If you watched the video it explains that the inflammation comes from slow breakdown of catecholamines. B2 increases neurotransmitters and I assume MB12 and Mfolate will be used up in the breakdown, especially if someone has the slow version of the enzymes.

Aha! Nope, I haven't watched it yet, because I'm finishing up a translation. I'm not having any more luck than you are at comprehending the big picture of COMT +/+ .