Julie Rehmeyer's 'Through the Shadowlands'
Writer Never Give Up talks about Julie Rehmeyer's new book "Through the Shadowlands: A Science Writer's Odyssey into an Illness Science Doesn't Understand" and shares an interview with Julie ...
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COMT++ ... has anyone come up with any supps that work for this mutation?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Bansaw, Jul 17, 2015.

  1. Bansaw

    Bansaw Senior Member

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    I saw my doc last week and she says that they've found supplements for the other mutations, but not the COMT ones. I am ++ for both my COMT's.
    Anyone had success dealing with their COMTs?
     
  2. ahmo

    ahmo Senior Member

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    Northcoast NSW, Australia
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  3. TheChosenOne

    TheChosenOne Senior Member

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    GABA + Magnesium works wonderfully.
    I'm gonna try lithium soon.
    I can tolerate hydroxycobalamin (1000 mcg) and methylfolate (400 mcg). I take methylcobalamin in very low doses.
     
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  4. Bansaw

    Bansaw Senior Member

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    Thanks Chosen...
    Do you have a natural source of GABA? My doc says I must try B12 adenosylcobalamin. She says this is the best form for my SNPs. That and possibly Hydro....
    I see you are like me, both your COMTs are +/+. Do you use the cirate form of Magnesium? Am I right in thinking that Magnesium just serves to calm you down a little, or does it do soemthing extra? I've been using Magnesium Lactate but I don't think its done anything tangible for me.
     
  5. TheChosenOne

    TheChosenOne Senior Member

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    You have MTRR/A66G+/+, so you might need some methylB12.
    I take GABA as a supplement. Yes, I use magnesium citrate. I've used magnesium oxide before, but apparently it's very bad for the intestines. Magnesium makes GABA more effective.
     
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